SCHEMBL608968

SCHEMBL608968

FC(F)(F)C(c1ccc(Cl)cc1)(c1ccc(Cl)cc1)C(F)(F)F

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.56
ESR2 Q92731 1/20 0.56
CYP19A1 P11511 8/20 0.45
LMNA P02545 1/20 0.44
CYP2A6 P11509 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
TSHR P16473 1/20 0.44
MAPK1 P28482 1/20 0.44
HIF1A Q16665 1/20 0.44
MIF P14174 1/20 0.37
HSD17B10 Q99714 1/20 0.36
KCNH2 Q12809 1/20 0.36
TMEM97 Q5BJF2 1/20 0.36
IDO1 P14902 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7929307 0.91 CYP19A1 (0.52) ESR1ESR2CYP19A1LMNACYP2A6
SCHEMBL7938023 0.89 ESR1 (0.78) ESR1ESR2CYP19A1LMNAMEN1
SCHEMBL9621264 0.89 ESR1 (0.46) ESR1ESR2CYP19A1LMNACYP2A6
SCHEMBL13050045 0.80 ALDH1A1 (0.39) ESR1ESR2CYP19A1MEN1KMT2A
SCHEMBL5350641 0.78 CYP19A1 (0.45) CYP19A1LMNACYP2A6MEN1KMT2A
SCHEMBL3671356 0.78 CYP19A1 (0.45) CYP19A1LMNACYP2A6MEN1KMT2A
SCHEMBL809388 0.78 MAPK1 (0.67) ESR1ESR2LMNAMAPK1
SCHEMBL5401000 0.77 LMNA (0.50) CYP19A1LMNACYP2A6MEN1KMT2A
SCHEMBL28777340 0.77 CYP19A1 (0.55) CYP19A1LMNACYP2A6MEN1KMT2A
SCHEMBL809832 0.77 LMNA (0.50) CYP19A1LMNACYP2A6MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108367529-B Lightweight flame retardant thermoplastic structures 施内勒公司 2021-02-05 CN claimed
EP-0306051-B1 Process for production of aromatic polyethers MITSUBISHI GAS CHEMICAL CO (JP) 1996-03-06 EP claimed
US-4952665-A Process for production of aromatic polyethers with alkali metal carbonate/bicarbonate/fluoride cocatalyst MITSUBISHI GAS CHEMICAL COMPANY, LTD. (JP) 1990-08-28 US claimed
EP-0306051-A1 Process for production of aromatic polyethers MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1989-03-08 EP claimed
US-20240218114-A1 ANION EXCHANGE RESIN AND ELECTROLYTE MEMBRANE UNIVERSITY OF YAMANASHI (JP) 2024-07-04 US disclosed
US-20240218114-A1 ANION EXCHANGE RESIN AND ELECTROLYTE MEMBRANE UNIVERSITY OF YAMANASHI (JP) 2024-07-04 US disclosed
CN-117304452-A Sulfonated polyphenylene ionomer, preparation method thereof and proton exchange membrane 河南大学 2023-12-29 CN disclosed
WO-2022230196-A1 ANION EXCHANGE RESIN AND ELECTROLYTE MEMBRANE 国立大学法人山梨大学 2022-11-03 WO disclosed
US-11173484-B2 Anion exchange resin, electrolyte membrane, binder for forming electrode catalyst layer, fuel cell electrode catalyst layer and fuel cell UNIVERSITY OF YAMANASHI (JP) 2021-11-16 US disclosed
CN-108367529-B Lightweight flame retardant thermoplastic structures 施内勒公司 2021-02-05 CN disclosed
US-20200230590-A1 ANION EXCHANGE RESIN, ELECTROLYTE MEMBRANE, BINDER FOR FORMING ELECTRODE CATALYST LAYER, FUEL CELL ELECTRODE CATALYST LAYER AND FUEL CELL UNIVERSITY OF YAMANASHI (JP) 2020-07-23 US disclosed
WO-2020017113-A1 POLYMER ELECTROLYTE, METHOD FOR PRODUCING SAME, POLYMER ELECTROLYTE MEMBRANE USING SAME, CATALYST LAYER, MEMBRANE/ELECTRODE ASSEMBLY AND FUEL CELL 国立大学法人山梨大学 2020-01-23 WO disclosed
EP-0192767-B1 DERIVATIVES OF DIPHENYLHEXAFLUOROPROPANE Hughes Aircraft Company (US) 1990-05-16 EP disclosed
EP-0306051-A1 Process for production of aromatic polyethers MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1989-03-08 EP disclosed
US-4722985-A Derivatives of diphenylhexafluoropropane and polymers thereof HUGHES AIRCRAFT COMPANY (US) 1988-02-02 US disclosed
US-4719258-A Derivatives of diphenylhexafluoropropane and resins thereof HUGHES AIRCRAFT COMPANY (US) 1988-01-12 US disclosed
US-4649207-A Derivatives of diphenylhexafluoropropane HUGHES AIRCRAFT COMPANY (US) 1987-03-10 US disclosed
EP-0092310-B1 BIS(HALOPHENYL)HEXAFLUOROPROPANES AND PROCESS FOR MAKING THE SAME Hughes Aircraft Company (US) 1985-07-24 EP disclosed
US-4503254-A HALOGENATION OF HYDROXY PRECURSOR WITH TRIPHENYLPHOSPHINE DIHALIDE HUGHES AIRCRAFT COMPANY (US) 1985-03-05 US disclosed
EP-0092310-A1 Bis(halophenyl)hexafluoropropanes and process for making the same Hughes Aircraft Company (US) 1983-10-26 EP disclosed