Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6091187 | 0.88 | SERPINE1 (0.44) | MAPK8NR4A2TBXAS1PLA2G2AKDM4E | |
| SCHEMBL6090931 | 0.83 | KMT2A (0.58) | KMT2AMAPK8PLA2G2AKDM4EMAPT | |
| SCHEMBL5746891 | 0.79 | KMT2A (0.52) | KMT2AMAPK8PLA2G2AKDM4EMAPT | |
| SCHEMBL11263827 | 0.71 | KMT2A (0.60) | KMT2APLA2G2ASMN1; SMN2 | |
| SCHEMBL4886339 | 0.71 | PLA2G2A (0.55) | KMT2AMAPK8S1PR3PLA2G2AKDM4E | |
| SCHEMBL11729659 | 0.70 | KMT2A (0.56) | KMT2AMAPK8KDM4EMAPTCYP1A2 | |
| SCHEMBL15074529 | 0.70 | MAPT (0.59) | KMT2ATBXAS1NPC1RAB9AL3MBTL1 | |
| SCHEMBL25761874 | 0.70 | TBXAS1 (0.45) | KMT2ATBXAS1S1PR3PLA2G2AGABRA1 | |
| SCHEMBL4893009 | 0.69 | PLA2G2A (0.51) | KMT2AMAPK8PLA2G2AKDM4EMAPT | |
| SCHEMBL5739485 | 0.69 | ACLY (0.53) | KMT2AMAPK8MAPTCYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060160879-A1 | Indoles useful in the treatment of inflammation | BIOLIPOX AB (SE) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160879-A1 | Indoles useful in the treatment of inflammation | IDO1, PTGS1, IDO2 | KMT2A 3542/4885MAPK8 3463/4885NR4A2 1637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.