Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20524537 | 0.83 | PDE5A (0.44) | RAB9AKDM4EAPOBEC3AAPOBEC3GTSHR | |
| SCHEMBL29101283 | 0.81 | CYSLTR2 (0.46) | RAB9AKDM4EAPOBEC3AAPOBEC3GTSHR | |
| SCHEMBL12426100 | 0.80 | ALDH1A1 (0.46) | TAAR1RAB9AKDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL16085821 | 0.80 | ALDH1A1 (0.46) | TAAR1RAB9AKDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL1882900 | 0.79 | TLR8 (0.46) | RAB9AKDM4EAPOBEC3AAPOBEC3GTSHR | |
| SCHEMBL1882899 | 0.79 | TLR8 (0.46) | RAB9AKDM4EAPOBEC3AAPOBEC3GTSHR | |
| SCHEMBL6090487 | 0.78 | HSD11B1 (0.43) | TAAR1RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL348173 | 0.78 | TRPA1 (0.46) | TAAR1KDM4ELMNA | |
| SCHEMBL21388957 | 0.76 | SIGMAR1 (0.42) | RAB9AKDM4EAPOBEC3AAPOBEC3GTSHR | |
| SCHEMBL15473593 | 0.75 | TAAR1 (0.48) | TAAR1RAB9AKDM4EAPOBEC3AAPOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006059210-A2 | FUSED BICYCLIC PYRROLS AS HMG-COA REDUCTASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2006-06-08 | — | — | WO | disclosed |