Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | SLC26A4 | O43511 | 2/20 | 0.54 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.53 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.45 |
| ▸ | FDPS | P14324 | 1/20 | 0.45 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6088483 | 0.88 | SLC26A4 (0.52) | NPC1RAB9ASLC26A4MEN1KMT2A | |
| SCHEMBL6088674 | 0.88 | SLC26A4 (0.63) | NPC1RAB9ASLC26A4MEN1KMT2A | |
| SCHEMBL6088897 | 0.86 | GABRA1 (0.52) | NPC1RAB9ASLC26A4PARP10PARP15 | |
| SCHEMBL4450809 | 0.85 | NR4A2 (0.58) | SLC26A4MEN1KMT2APTGER4NR4A2 | |
| SCHEMBL6087927 | 0.85 | MRGPRX4 (0.53) | NPC1RAB9ASLC26A4NR4A2 | |
| SCHEMBL6089332 | 0.83 | NR4A2 (0.67) | NPC1RAB9ASLC26A4MEN1KMT2A | |
| SCHEMBL6090532 | 0.83 | SLC26A4 (0.51) | NPC1RAB9ASLC26A4MEN1KMT2A | |
| SCHEMBL4451992 | 0.82 | SLC26A4 (0.53) | NPC1RAB9ASLC26A4MEN1KMT2A | |
| SCHEMBL7222374 | 0.81 | NR4A2 (0.68) | NPC1RAB9APARP10PARP15FFAR1 | |
| SCHEMBL5725146 | 0.81 | CYSLTR1 (0.67) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7005440-B1 | Therapeutic uses of tri-aryl acid derivatives | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2006-02-28 | — | — | US | disclosed |
| CN-1183113-C | Tri-aryl acid derivatives as PPAR receptor ligands | ���ĵ�˹ҩ��¹�����˾ | 2005-01-05 | — | — | CN | disclosed |
| CN-1356983-A | Tri-aryl acid derivatives as PPAR receptor ligands | AVENTIS PHARM PROD INC (DE) | 2002-07-03 | — | — | CN | disclosed |