Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC26A4 | O43511 | 2/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6088483 | 0.89 | SLC26A4 (0.52) | SLC26A4NR4A2NPC1RAB9AMAOB | |
| SCHEMBL6088674 | 0.89 | SLC26A4 (0.63) | SLC26A4NR4A2NPC1RAB9AMAOB | |
| SCHEMBL6091862 | 0.86 | SLC26A4 (0.52) | SLC26A4NR4A2NPC1RAB9AMAOB | |
| SCHEMBL6088781 | 0.86 | MAOB (0.44) | SLC26A4NR4A2NPC1RAB9AMAOB | |
| SCHEMBL4450809 | 0.86 | NR4A2 (0.58) | SLC26A4NR4A2MAOBPTGER4MRGPRX4 | |
| SCHEMBL4451992 | 0.86 | SLC26A4 (0.53) | SLC26A4NR4A2NPC1RAB9AMAOB | |
| SCHEMBL6089332 | 0.84 | NR4A2 (0.67) | SLC26A4NR4A2NPC1RAB9AMAOB | |
| SCHEMBL6087987 | 0.83 | SLC26A4 (0.46) | SLC26A4NR4A2NPC1RAB9AMAOB | |
| SCHEMBL6092100 | 0.83 | RXRA (0.51) | SLC26A4NR4A2MAOBPTGER4MRGPRX4 | |
| SCHEMBL6090535 | 0.83 | NPC1 (0.55) | SLC26A4NR4A2NPC1RAB9APTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7005440-B1 | Therapeutic uses of tri-aryl acid derivatives | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2006-02-28 | — | — | US | disclosed |