Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.32 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.30 |
| ▸ | PYGL | P06737 | 1/20 | 0.30 |
| ▸ | PYGM | P11217 | 1/20 | 0.30 |
| ▸ | TYMS | P04818 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6094362 | 0.81 | FFAR1 (0.44) | FFAR1KMT2A | |
| SCHEMBL6092194 | 0.79 | KDM4E (0.37) | FFAR1ALDH1A1NPC1RAB9AL3MBTL1 | |
| SCHEMBL4471486 | 0.77 | MEN1 (0.41) | PARP1ALDH1A1MDM2PARP2MEN1 | |
| SCHEMBL4475021 | 0.77 | MDM2 (0.39) | PARP1FFAR1ALDH1A1NOD2NOD1 | |
| SCHEMBL6092904 | 0.76 | FFAR1 (0.36) | FFAR1ALDH1A1MEN1KMT2AATM | |
| SCHEMBL6095195 | 0.76 | TRPA1 (0.33) | TRPA1 | |
| SCHEMBL6092919 | 0.75 | MDM2 (0.39) | FFAR1MDM2TP53TRPA1 | |
| SCHEMBL6092501 | 0.75 | KDM4E (0.36) | FFAR1ALDH1A1MEN1KMT2A | |
| SCHEMBL6090274 | 0.74 | KDM4E (0.35) | FFAR1ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL28746675 | 0.73 | LMNA (0.35) | PARP1ALDH1A1NOD2NOD1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060148880-A1 | Isoindolone derivatives, preparation process and intermediates of this process, their use as medicaments, and pharmaceutical compositions comprising them | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2006-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060148880-A1 | Isoindolone derivatives, preparation process and intermediates of this process, their use as medicaments, and pharmaceutical compositions comprising them | TNNI3, NDUFB3, NDUFB11 | PARP1 2985/4885FFAR1 2288/4885ALDH1A1 243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.