Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.45 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.45 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6090897 | 0.84 | P2RX7 (0.46) | P2RX7ALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL18317449 | 0.84 | RAB9A (0.45) | P2RX7ALDH1A1LMNAMAPTRECQL | |
| SCHEMBL6092329 | 0.84 | KMT2A (0.48) | EPHX1P2RX7ALDH1A1LMNAHTT | |
| SCHEMBL6092092 | 0.84 | TNFRSF1A (0.47) | P2RX7ALDH1A1MAPTNPSR1HTT | |
| SCHEMBL1769995 | 0.82 | TSHR (0.56) | P2RX7ALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL4728169 | 0.82 | TSHR (0.56) | P2RX7ALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL6091478 | 0.82 | FAAH (0.61) | FAAHMAOBEPHX2 | |
| SCHEMBL4731777 | 0.80 | RAB9A (0.51) | P2RX7ALDH1A1LMNAMAPTPLIN1 | |
| SCHEMBL6093069 | 0.80 | ALDH1A1 (0.43) | ALDH1A1LMNAMAPTNPSR1HTT | |
| SCHEMBL6093038 | 0.80 | HDAC1 (0.41) | P2RX7ALDH1A1LMNAMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060074083-A1 | Cyclic and acyclic propenones for treating CNS disorders | MERZ PHARMA GMBH & CO. KGAA (DE) | 2006-04-06 | — | — | US | claimed |
| US-20060074083-A1 | Cyclic and acyclic propenones for treating CNS disorders | MERZ PHARMA GMBH & CO. KGAA (DE) | 2006-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060074083-A1 | Cyclic and acyclic propenones for treating CNS disorders | PMP22, ADCYAP1R1, CYP11B2 | FAAH 459/4885EPHX1 1335/4885P2RX7 373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.