Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 10/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 2/20 | 0.48 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6088473 | 0.92 | HIF1A (0.57) | HIF1AMRGPRX4MAOB | |
| SCHEMBL6091367 | 0.90 | FFAR1 (0.53) | FFAR1FFAR4LTA4HPLA2G2AMRGPRX4 | |
| SCHEMBL6088329 | 0.85 | MAOB (0.52) | FFAR1HIF1AMRGPRX4MAOB | |
| SCHEMBL6089138 | 0.85 | MAOB (0.59) | FFAR1FFAR4MRGPRX4MAOB | |
| SCHEMBL6088416 | 0.85 | ADAM17 (0.47) | HIF1AMRGPRX4 | |
| SCHEMBL6088959 | 0.83 | MAOB (0.48) | HIF1AMRGPRX4MAOB | |
| SCHEMBL6087974 | 0.81 | HIF1A (0.58) | HIF1AMAOB | |
| SCHEMBL6088324 | 0.81 | MAOB (0.45) | HIF1AMRGPRX4MAOB | |
| SCHEMBL6090155 | 0.81 | NR4A2 (0.57) | FFAR1FFAR4HIF1AMAOB | |
| SCHEMBL6088841 | 0.81 | MAPT (0.50) | HIF1AMRGPRX4MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7005440-B1 | Therapeutic uses of tri-aryl acid derivatives | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2006-02-28 | — | — | US | disclosed |
| EP-1177176-A1 | TRI-ARYL ACID DERIVATIVES AS PPAR RECEPTOR LIGANDS | Aventis Pharma Deutschland GmbH (DE) | 2002-02-06 | — | — | EP | disclosed |
| WO-2000064876-A1 | TRI-ARYL ACID DERIVATIVES AS PPAR RECEPTOR LIGANDS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-11-02 | — | — | WO | disclosed |