Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.60 |
| ▸ | MAOB | P27338 | 11/20 | 0.58 |
| ▸ | MAOA | P21397 | 3/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.50 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4450809 | 0.89 | NR4A2 (0.58) | MRGPRX4MAOBALDH1A1SMN1; SMN2 | |
| SCHEMBL6089138 | 0.88 | MAOB (0.59) | MRGPRX4MAOBMAOAFFAR1FFAR4 | |
| SCHEMBL6091367 | 0.85 | FFAR1 (0.53) | MRGPRX4FFAR1FFAR4 | |
| SCHEMBL6088674 | 0.83 | SLC26A4 (0.63) | MAOBFFAR1NPC1RAB9APTGER1 | |
| SCHEMBL6087927 | 0.83 | MRGPRX4 (0.53) | MRGPRX4MAOBNPC1RAB9A | |
| SCHEMBL6092100 | 0.82 | RXRA (0.51) | MRGPRX4MAOBSMN1; SMN2 | |
| SCHEMBL6087956 | 0.81 | PTGER4 (0.55) | MRGPRX4MAOBFFAR1FFAR4 | |
| SCHEMBL6088680 | 0.81 | NR4A2 (0.62) | MRGPRX4MAOBMAOANPC1RAB9A | |
| SCHEMBL6090532 | 0.81 | SLC26A4 (0.51) | MRGPRX4MAOBFFAR1NPC1RAB9A | |
| SCHEMBL4451992 | 0.80 | SLC26A4 (0.53) | MRGPRX4MAOBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7005440-B1 | Therapeutic uses of tri-aryl acid derivatives | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2006-02-28 | — | — | US | disclosed |