Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.52 |
| ▸ | UTS2R | Q9UKP6 | 5/20 | 0.48 |
| ▸ | KLK7 | P49862 | 4/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 4/20 | 0.44 |
| ▸ | CASR | P41180 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5465030 | 0.76 | UTS2R (0.81) | UTS2R | |
| SCHEMBL4730538 | 0.74 | CNR1 (0.40) | CNR1UTS2RCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL3660216 | 0.73 | DRD2 (0.46) | CNR1UTS2ROPRM1KMT2AMEN1 | |
| SCHEMBL4732737 | 0.73 | UTS2R (0.61) | UTS2R | |
| SCHEMBL4729141 | 0.72 | TMEM97 (0.55) | UTS2ROPRM1KMT2AOPRD1 | |
| SCHEMBL10693205 | 0.72 | KLK7 (0.53) | CNR1KLK7CNR2KMT2A | |
| SCHEMBL4731502 | 0.72 | UTS2R (0.55) | UTS2RKMT2AMEN1 | |
| SCHEMBL6093119 | 0.70 | OPRM1 (0.43) | UTS2ROPRM1KMT2AOPRD1MEN1 | |
| SCHEMBL6091970 | 0.70 | UTS2R (0.59) | UTS2RCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL9502645 | 0.69 | PKM (0.59) | KLK7KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006135694-A2 | UII-MODULATING COMPOUNDS AND THEIR USE | ACADIA PHARMACEUTICALS INC. (US) | 2006-12-21 | — | — | WO | disclosed |