Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16909527 | 0.78 | ITGB3 (0.30) | — | |
| SCHEMBL15551712 | 0.77 | HRH3 (0.44) | HRH3ALDH1A1 | |
| SCHEMBL28613618 | 0.75 | — | — | |
| SCHEMBL28921670 | 0.75 | — | — | |
| SCHEMBL692210 | 0.74 | MEN1 (0.45) | ALDH1A1 | |
| SCHEMBL7005716 | 0.72 | CDC42 (0.32) | — | |
| SCHEMBL5435516 | 0.72 | HRH3 (0.41) | HRH3ALDH1A1 | |
| SCHEMBL16909738 | 0.71 | HRH3 (0.32) | HRH3 | |
| SCHEMBL20585124 | 0.69 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL1008201 | 0.69 | RBP4 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105507-B2 | Cyclohexane derivatives and their use as therapeutic agents | MERCK SHARP & DOHME LIMITED (GB) | 2006-09-12 | — | — | US | disclosed |
| US-20030236250-A1 | Cyclohexane derivatives and their use as therapeutic agents | MERCK SHARP & DOHME LTD. (GB) | 2003-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030236250-A1 | Cyclohexane derivatives and their use as therapeutic agents | CNR2, CNR1, HTR1A | HRH3 116/4885ALDH1A1 1452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.