Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 2/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6925999 | 0.92 | ACHE (0.43) | NR3C1ACHENPY1RHTR4TLR7 | |
| Trifluoroacetic Acid SCHEMBL6923561 | 0.85 | HTR4 (0.41) | NR3C1ACHENPY1RHTR4TLR7 | |
| SCHEMBL27552337 | 0.82 | ACHE (0.48) | NR3C1ACHETLR7LMNATSHR | |
| SCHEMBL6838687 | 0.82 | HTR4 (0.41) | NR3C1ACHENPY1RHTR4TLR7 | |
| SCHEMBL6929031 | 0.82 | SLC6A4 (0.40) | NR3C1NPY1RLMNATSHRHTT | |
| SCHEMBL6925393 | 0.81 | ACHE (0.46) | NR3C1ACHETLR7LMNATSHR | |
| SCHEMBL6926216 | 0.81 | NR3C1 (0.38) | NR3C1ACHENPY1RHTR4LMNA | |
| SCHEMBL6096772 | 0.80 | TLR7 (0.56) | ACHENPY1RHTR4TLR7LMNA | |
| Hydrochloric Acid SCHEMBL6929408 | 0.79 | TLR7 (0.55) | ACHENPY1RHTR4TLR7LMNA | |
| SCHEMBL6929405 | 0.78 | KDM4E (0.42) | NR3C1NPY1RACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518265-B1 | 1H-imidazopyridine derivatives | HOKURIKU SEIYAKU CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-1104764-A1 | 1H-IMIDAZOPYRIDINE DERIVATIVES | HOKURIKU SEIYAKU CO., LTD. (JP) | 2001-06-06 | — | — | EP | disclosed |