Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7347214 | 0.85 | PSIP1 (0.52) | PSIP1TRPA1HSD11B1POLBMMP13 | |
| SCHEMBL15214393 | 0.84 | PSIP1 (0.50) | PSIP1HSD11B1POLBMMP13MMP1 | |
| SCHEMBL20780856 | 0.84 | PSIP1 (0.55) | PSIP1HSD11B1POLBMMP13MMP1 | |
| SCHEMBL28138744 | 0.83 | HSD11B1 (0.49) | PSIP1HSD11B1POLBMMP13MMP1 | |
| SCHEMBL5276301 | 0.81 | GAA (0.48) | ALDH1A1HTTHSD17B10SMN1; SMN2GAA | |
| SCHEMBL5950906 | 0.81 | GAA (0.48) | ALDH1A1HTTHSD17B10SMN1; SMN2GAA | |
| SCHEMBL25015902 | 0.81 | PSIP1 (0.52) | PSIP1HSD11B1POLBMMP13MMP1 | |
| SCHEMBL7437440 | 0.81 | PSIP1 (0.47) | PSIP1HSD11B1POLBMMP13MMP1 | |
| SCHEMBL7347205 | 0.79 | PSIP1 (0.54) | PSIP1HSD11B1POLBMMP13MMP1 | |
| SCHEMBL2444476 | 0.79 | PSIP1 (0.59) | PSIP1HSD11B1POLBMMP13MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7101892-B2 | Sulfone derivatives as 5-HT7 receptor ligands | MERCK SHARP & DOHME LTD. | 2006-09-05 | — | — | US | disclosed |
| US-20040229864-A1 | Sulfone derivatives as 5-HT7 receptor ligands | MERCK SHARP & DOHME LTD. (GB) | 2004-11-18 | — | — | US | disclosed |
| US-4603208-A | MODIFIED POLYISOPRENE CONVERTED TO DOLICHOLS | KURARAY CO., LTD. (JP) | 1986-07-29 | — | — | US | disclosed |
| EP-0087638-B1 | POLYPRENYL COMPOUNDS AND PREPARATION THEREOF | KURARAY CO., LTD. (JP) | 1985-06-05 | — | — | EP | disclosed |
| EP-0087638-A1 | Polyprenyl compounds and preparation thereof | KURARAY CO., LTD. (JP) | 1983-09-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040229864-A1 | Sulfone derivatives as 5-HT7 receptor ligands | HTR7, HTR2C, HTR1A | PSIP1 1776/4885TRPA1 416/4885HSD11B1 767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.