Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 10/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL650647 | 0.81 | NFE2L2 (0.47) | LMNANFE2L2 | |
| SCHEMBL28502273 | 0.81 | NFE2L2 (0.43) | LMNAKDM4ENFE2L2HTTMET | |
| SCHEMBL950477 | 0.79 | NFE2L2 (0.45) | LMNAKMT2ANFE2L2MET | |
| Hydrochloric Acid SCHEMBL7085595 | 0.79 | NFE2L2 (0.42) | LMNAKDM4ENFE2L2HTTMET | |
| SCHEMBL14120534 | 0.77 | CA2 (0.45) | LMNAKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL390770 | 0.77 | KMT2A (0.56) | LMNAKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL8537341 | 0.77 | FTO (0.49) | KMT2AKDM4EMEN1ALDH1A1CA1 | |
| SCHEMBL10480797 | 0.77 | CA1 (0.58) | LMNAKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL27327034 | 0.76 | NFE2L2 (0.44) | LMNAKMT2ANFE2L2MET | |
| SCHEMBL30727252 | 0.76 | NFE2L2 (0.44) | LMNAKMT2ANFE2L2MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4490380-A | 3-CHLORO-2-PYRIDINE SULFONAMIDE; MITICIDES; LARVACIDES | THE DOW CHEMICAL COMPANY (US) | 1984-12-25 | — | — | US | claimed |
| CN-106928134-B | A kind of preparation facilities and synthetic method of nicosulfuron intermediate | 山东理工大学 | 2019-07-16 | — | — | CN | disclosed |
| CN-106928134-A | The preparation facilities and synthetic method of a kind of nicosulfuron intermediate | 山东理工大学 | 2017-07-07 | — | — | CN | disclosed |
| CN-103012258-A | Production technology of 2-sulfamide-N,N-dimethylnicotinamide | UNIV CHANGZHOU | 2013-04-03 | — | — | CN | disclosed |
| US-7001917-B2 | Pyrazole compounds as anti-inflammatory and analgesic agents | WARNER LAMBERT COMPANY LLC (US) | 2006-02-21 | — | — | US | disclosed |
| EP-1495005-A1 | PYRAZOLE COMPOUNDS AS ANTI-INFLAMMATORY AND ANALGESIC AGENTS | Pfizer Japan Inc. (JP) | 2005-01-12 | — | — | EP | disclosed |
| US-20040019045-A1 | 2-(4-(4-(4-Fluorophenyl)-3,5-imethyl-1H-pyrazol-1-yl)phenyl) ethyl (4-methylphenyl)sulfonylcarbamate ammonium salt, e.g., as an antagonist for Prostoglandin E receptor; analgesics; antipyretics; antiinflammatory agents | HIRANO MISATO (JP) | 2004-01-29 | — | — | US | disclosed |
| WO-2003087061-A1 | PYRAZOLE COMPOUNDS AS ANTI-INFLAMMATORY AND ANALGESIC AGENTS | PFIZER JAPAN INC. (JP) | 2003-10-23 | — | — | WO | disclosed |
| EP-0271208-B1 | HERBICIDAL PYRIDINE N-OXIDE SULFONYLUREAS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-04-21 | — | — | EP | disclosed |
| US-4900353-A | PRE-AND POSTEMERGENCE HERBICIDES; PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-02-13 | — | — | US | disclosed |
| US-4789465-A | Herbicidal pyridine N-oxide sulfonylureas | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-12-06 | — | — | US | disclosed |
| EP-0271208-A1 | Herbicidal pyridine N-oxide sulfonylureas | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-06-15 | — | — | EP | disclosed |
| WO-1988003528-A2 | HERBICIDAL PYRIDINE N-OXIDE SULFONYLUREAS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-05-19 | — | — | WO | disclosed |
| US-4490380-A | 3-CHLORO-2-PYRIDINE SULFONAMIDE; MITICIDES; LARVACIDES | THE DOW CHEMICAL COMPANY (US) | 1984-12-25 | — | — | US | disclosed |
| US-4490380-A | 3-CHLORO-2-PYRIDINE SULFONAMIDE; MITICIDES; LARVACIDES | THE DOW CHEMICAL COMPANY (US) | 1984-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040019045-A1 | 2-(4-(4-(4-Fluorophenyl)-3,5-imethyl-1H-pyrazol-1-yl)phenyl) ethyl (4-methylphenyl)sulfonylcarbamate ammonium salt, e.g., as an antagonist for Prostoglandin E receptor; analgesics; antipyretics; antiinflammatory agents | PTGER1, PTGS1, PTGIR | LMNA 4316/4885KMT2A 2815/4885KDM4E 624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.