Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28502273 | 0.83 | NFE2L2 (0.43) | NFE2L2LMNA | |
| SCHEMBL6098339 | 0.81 | LMNA (0.50) | NFE2L2LMNA | |
| SCHEMBL950477 | 0.81 | NFE2L2 (0.45) | NFE2L2LMNA | |
| Hydrochloric Acid SCHEMBL7085595 | 0.81 | NFE2L2 (0.42) | NFE2L2LMNA | |
| SCHEMBL30727252 | 0.78 | NFE2L2 (0.44) | NFE2L2LMNA | |
| SCHEMBL27327034 | 0.78 | NFE2L2 (0.44) | NFE2L2LMNA | |
| SCHEMBL1039344 | 0.77 | NOS3 (0.43) | NFE2L2 | |
| SCHEMBL9734435 | 0.77 | TRPV4 (0.42) | NFE2L2 | |
| SCHEMBL30665364 | 0.77 | TRPV4 (0.42) | NFE2L2LMNA | |
| SCHEMBL937654 | 0.77 | TRPV4 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1048654-B1 | Process for the preparation of chloropyridine sulfonyl chloride | RUETGERS ORGANICS GMBH (DE) | 2003-07-30 | — | — | EP | claimed |
| US-6310214-B1 | FROM HYDROXYPYRIDINESULPHONIC ACIDS COMPRISING PASSING CHLORINE GAS INTO A MIXTURE OF A HYDROXYPYRIDINESULPHONIC ACID AND OF PHOSPHORUS TRICHLORIDE; HEATING; DISTILLATION | RUETGERS ORGANICS GMBH (DE) | 2001-10-30 | — | — | US | claimed |
| EP-1048654-A2 | Process for the preparation of chloropyridine sulfonyl chloride | Rütgers Organics GmbH (DE) | 2000-11-02 | — | — | EP | claimed |
| WO-2000063177-A1 | METHOD OF PRODUCING CHLOROPYRIDINE SULFONIC ACID CHLORIDES | RÜTGERS ORGANICS GMBH (DE) | 2000-10-26 | — | — | WO | claimed |
| US-9174964-B2 | AMPK-activating piperidinyloxy-substituted 2,3-dihydro-1H-indene-1-amine compounds and pharmaceutical compositions including the same | RIGEL PHARMACEUTICALS, INC. (US) | 2015-11-03 | — | — | US | disclosed |
| US-20150252019-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | CELGENE AVILOMICS RESEARCH, INC. | 2015-09-10 | — | — | US | disclosed |
| EP-2231600-B1 | CARBOXAMIDE, SULFONAMIDE AND AMINE COMPOUNDS FOR METABOLIC DISORDERS | RIGEL PHARMACEUTICALS INC (US) | 2015-07-29 | — | — | EP | disclosed |
| US-9067929-B2 | Heterocyclic compounds and uses thereof | CELGENE AVILOMICS RESEARCH, INC. (US) | 2015-06-30 | — | — | US | disclosed |
| CN-101039904-B | Is suitable for treating dopamine D3Heterocyclic compounds for receptor-modulated responsive disorders | ABBOTT GMBH & CO KG | 2014-09-24 | — | — | CN | disclosed |
| US-20140073661-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | CELGENE AVILOMICS RESEARCH, INC. (US) | 2014-03-13 | — | — | US | disclosed |
| US-20140051673-A1 | AMPK-Activating Heterocycloalkyloxy(Hetero)Aryl Carboxamide, Sulfonamide And Amine Compounds And Methods For Using The Same | RIGEL PHARMACEUTICALS, INC. (US) | 2014-02-20 | — | — | US | disclosed |
| US-8586600-B2 | Heterocyclic compounds and uses thereof | CELGENE AVILOMICS RESEARCH, INC. (US) | 2013-11-19 | — | — | US | disclosed |
| US-6310214-B1 | FROM HYDROXYPYRIDINESULPHONIC ACIDS COMPRISING PASSING CHLORINE GAS INTO A MIXTURE OF A HYDROXYPYRIDINESULPHONIC ACID AND OF PHOSPHORUS TRICHLORIDE; HEATING; DISTILLATION | RUETGERS ORGANICS GMBH (DE) | 2001-10-30 | — | — | US | disclosed |
| US-6310214-B1 | FROM HYDROXYPYRIDINESULPHONIC ACIDS COMPRISING PASSING CHLORINE GAS INTO A MIXTURE OF A HYDROXYPYRIDINESULPHONIC ACID AND OF PHOSPHORUS TRICHLORIDE; HEATING; DISTILLATION | RUETGERS ORGANICS GMBH (DE) | 2001-10-30 | — | — | US | disclosed |
| WO-2000063177-A8 | METHOD OF PRODUCING CHLOROPYRIDINE SULFONIC ACID CHLORIDES | RUETGERS ORGANICS GMBH (DE) | 2001-02-22 | — | — | WO | disclosed |
| EP-1048654-A3 | Process for the preparation of chloropyridine sulfonyl chloride | Rütgers Organics GmbH (DE) | 2000-11-08 | — | — | EP | disclosed |
| EP-1048654-A2 | Process for the preparation of chloropyridine sulfonyl chloride | Rütgers Organics GmbH (DE) | 2000-11-02 | — | — | EP | disclosed |
| WO-2000063177-A1 | METHOD OF PRODUCING CHLOROPYRIDINE SULFONIC ACID CHLORIDES | RÜTGERS ORGANICS GMBH (DE) | 2000-10-26 | — | — | WO | disclosed |
| WO-1997046553-A1 | THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1997-12-11 | — | — | WO | disclosed |
| US-4490380-A | 3-CHLORO-2-PYRIDINE SULFONAMIDE; MITICIDES; LARVACIDES | THE DOW CHEMICAL COMPANY (US) | 1984-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150252019-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | ABCG2, CYP3A5, CYP3A43 | NFE2L2 2429/4885LMNA 1530/4885 |
| US-20140051673-A1 | AMPK-Activating Heterocycloalkyloxy(Hetero)Aryl Carboxamide, Sulfonamide And Amine Compounds And Methods For Using The Same | PRKAA1, PRKAA2, PRKAG1 | NFE2L2 687/4885LMNA 2643/4885 |
| US-20140073661-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | ABCG2, CYP3A5, CYP3A43 | NFE2L2 2429/4885LMNA 1530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.