SCHEMBL609848

SCHEMBL609848

CCN(CC)c1cccc(C(=S)c2ccccc2)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.53
CYP3A4 P08684 1/20 0.53
PTPN1 P18031 1/20 0.42
MAPT P10636 6/20 0.42
MEN1 O00255 5/20 0.42
KMT2A Q03164 5/20 0.42
TSHR P16473 2/20 0.42
LMNA P02545 1/20 0.42
GAA P10253 3/20 0.41
MAPK1 P28482 3/20 0.41
HTT P42858 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.40
CNR2 P34972 2/20 0.40
HPGD P15428 1/20 0.40
MAOB P27338 1/20 0.40
PKM P14618 2/20 0.39
NOX1 Q9Y5S8 2/20 0.39
KDM4E B2RXH2 2/20 0.39
THRB P10828 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL610430 0.84 TDP1 (0.53) ALDH1A1CYP3A4MAPTMEN1KMT2A
SCHEMBL609166 0.80 KMT2A (0.51) ALDH1A1MAPTMEN1KMT2ATSHR
SCHEMBL610585 0.79 L3MBTL1 (0.57) ALDH1A1CYP3A4MAPTMEN1KMT2A
SCHEMBL609060 0.79 ALDH1A1 (0.58) ALDH1A1CYP3A4PTPN1MAPTMEN1
SCHEMBL872529 0.79 ALDH1A1 (0.56) ALDH1A1CYP3A4MAPTMEN1KMT2A
SCHEMBL13498625 0.78 ALDH1A1 (0.51) ALDH1A1CYP3A4PTPN1MAPTMEN1
SCHEMBL759763 0.78 ALDH1A1 (0.51) ALDH1A1CYP3A4PTPN1MAPTMEN1
SCHEMBL14283593 0.78 ALDH1A1 (0.51) ALDH1A1CYP3A4PTPN1MAPTMEN1
SCHEMBL2742811 0.77 ALDH1A1 (0.58) ALDH1A1CYP3A4PTPN1MAPTMEN1
SCHEMBL611209 0.75 ALDH1A1 (0.52) ALDH1A1CYP3A4MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2857446-B1 TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2018-03-07 EP disclosed
US-9790359-B2 Tread rubber composition and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2017-10-17 US disclosed
CN-104334629-B Rubber composition for tire tread and pneumatic tire 住友橡胶工业株式会社 2016-08-24 CN disclosed
US-20150099823-A1 TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2015-04-09 US disclosed
EP-2857446-A1 TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE Sumitomo Rubber Industries, Ltd. (JP) 2015-04-08 EP disclosed
CN-104334629-A Tread rubber composition and pneumatic tire SUMITOMO RUBBER IND 2015-02-04 CN disclosed
US-8334339-B2 Conjugated diene-based polymer, conjugated diene-based polymer composition, and process for producing conjugated diene-based polymer SUMITOMO CHEMICAL CO., LTD. (JP) 2012-12-18 US disclosed
US-20120041134-A1 CONJUGATED DIENE-BASED POLYMER, CONJUGATED DIENE-BASED POLYMER COMPOSITION, AND PROCESS FOR PRODUCING CONJUGATED DIENE-BASED POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-16 US disclosed