Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1006035 | 0.90 | SIGMAR1 (0.42) | SIGMAR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL16924863 | 0.70 | LMNA (0.61) | SIGMAR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL2052260 | 0.70 | SMN1; SMN2 (0.44) | SIGMAR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL569307 | 0.70 | LMNA (0.61) | SIGMAR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL577708 | 0.69 | LMNA (0.58) | SIGMAR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL576673 | 0.69 | LMNA (0.58) | SIGMAR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL14500221 | 0.69 | LMNA (0.58) | SIGMAR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL2046994 | 0.67 | LMNA (0.50) | SIGMAR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL20396065 | 0.65 | SIGMAR1 (0.39) | SIGMAR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL18228234 | 0.65 | L3MBTL1 (0.61) | SIGMAR1MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7084222-B2 | Ruthenium complexes, process for preparation thereof, and processes for producing open-ring polymer of cycloolefins and hydrogenation products thereof by using the complex as catalyst | ZEON CORPORATION (JP) | 2006-08-01 | — | — | US | disclosed |