SCHEMBL1006035

SCHEMBL1006035

[C]1N(c2ccccc2)CCN1c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 5/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
LMNA P02545 2/20 0.41
HTR3E A5X5Y0 1/20 0.41
HTR3B O95264 1/20 0.41
ADRB1 P08588 1/20 0.41
HTR3A P46098 1/20 0.41
HTR3D Q70Z44 1/20 0.41
HTR3C Q8WXA8 1/20 0.41
CHRNA7 P36544 2/20 0.38
ALOX15 P16050 2/20 0.38
CYP3A4 P08684 1/20 0.38
CHRNB2 P17787 1/20 0.38
NFKB1 P19838 1/20 0.38
MAPK1 P28482 1/20 0.38
CHRNA3 P32297 1/20 0.38
CHRNA4 P43681 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6098689 0.90 SIGMAR1 (0.39) SIGMAR1MEN1KMT2ANPC1RAB9A
SCHEMBL7250087 0.72 CHRNA7 (0.35) SIGMAR1MEN1KMT2ANPC1RAB9A
SCHEMBL576814 0.67 LMNA (0.67) SIGMAR1MEN1KMT2ARAB9ALMNA
SCHEMBL385012 0.67
SCHEMBL164538 0.67 LMNA (0.67) SIGMAR1MEN1KMT2ARAB9ALMNA
SCHEMBL16924853 0.67 LMNA (0.67) SIGMAR1MEN1KMT2ARAB9ALMNA
SCHEMBL576454 0.67 LMNA (0.67) SIGMAR1MEN1KMT2ARAB9ALMNA
SCHEMBL1005413 0.65 ADRB1 (0.48) MEN1KMT2ALMNAADRB1SMN1; SMN2
SCHEMBL7258870 0.65 LMNA (0.64) SIGMAR1MEN1KMT2ARAB9ALMNA
SCHEMBL1029480 0.64 MEN1 (0.32) SIGMAR1MEN1KMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8933242-B2 Metal complexes, their application and methods of carrying out of metathesis reaction APEIRON SYNTHESIS S.A. (PL) 2015-01-13 US claimed
US-20140005408-A1 METAL COMPLEXES, THEIR APPLICATION AND METHODS OF CARRYING OUT OF METATHESIS REACTION APEIRON SYNTHESIS S.A. (PL) 2014-01-02 US claimed
WO-2023106405-A1 COMPOUND, ORGANIC SEMICONDUCTOR MATERIAL, AND ORGANIC ELECTRONIC DEVICE 国立大学法人大阪大学 2023-06-15 WO disclosed
WO-2023106404-A1 POLYMER COMPOUND, ORGANIC SEMICONDUCTOR MATERIAL, AND ORGANIC ELECTRONIC DEVICE 国立大学法人大阪大学 2023-06-15 WO disclosed
WO-2023068017-A1 ORGANIC SEMICONDUCTOR MATERIAL 東洋紡株式会社 2023-04-27 WO disclosed
EP-2826802-B1 METHOD FOR PRODUCING RING-OPENING METATHESIS POLYMER HYDRIDE, AND RESIN COMPOSITION ZEON CORP (JP) 2021-03-10 EP disclosed
US-10211401-B2 Organic semiconductor material TOYOBO CO., LTD. (JP) 2019-02-19 US disclosed
US-20180127520-A1 METHOD FOR PRODUCING RING-OPENING METATHESIS POLYMER HYDRIDE, AND RESIN COMPOSITION ZEON CORPORATION (JP) 2018-05-10 US disclosed
US-9850325-B2 Method for producing ring-opening metathesis polymer hydride, and resin composition ZEON CORPORATION (JP) 2017-12-26 US disclosed
EP-2975017-B1 LEAVING SUBSTITUENT-CONTAINING COMPOUND, ORGANIC SEMICONDUCTOR MATERIAL, ORGANIC SEMICONDUCTOR FILM CONTAINING THE MATERIAL, ORGANIC ELECTRONIC DEVICE CONTAINING THE FILM, METHOD FOR PRODUCING FILM-LIKE PRODUCT, PI-ELECTRON CONJUGATED COMPOUND AND METHOD FOR PRODUCING THE PI-ELECTRON CONJUGATED COMPOUND RICOH CO LTD (JP) 2017-11-08 EP disclosed
US-20170069845-A1 ORGANIC SEMICONDUCTOR MATERIAL TOYOBO CO., LTD. (JP) 2017-03-09 US disclosed
WO-2003097562-A2 HIGH ACTIVITY METAL CARBENE METATHESIS CATALYSTS GENERATED USING A THERMALLY ACTIVATED N-HETEROCYCLIC CARBENE PRECURSOR CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2003-11-27 WO disclosed
US-20030144437-A1 High activity metal carbene metathesis catalysts generated using a thermally activated N-heterocyclic carbene precursor STERLING JA, L.C. 2003-07-31 US disclosed
US-20030083445-A1 High activity metal carbene metathesis catalysts generated using a thermally activated N-heterocyclic carbene precursor STERLING JA, L.C. 2003-05-01 US disclosed
US-20030050406-A1 Process for producing hydrogenated product of cyclic olefin polymer prepared through ring-opening polymerization ZEON CORPORATION 2003-03-13 US disclosed
US-20030018138-A1 Copolymer formed by ring -opening polymerization, product of hydrogenation of copolymer formed by ring-opening polymerization, and process for producing these ZEON CORPORATION (JP) 2003-01-23 US disclosed
EP-1275675-A1 COPOLYMER FORMED BY RING-OPENING POLYMERIZATION, PRODUCT OF HYDROGENATION OF COPOLYMER FORMED BY RING-OPENING POLYMERIZATION, AND PROCESSES FOR PRODUCING THESE Zeon Corporation (JP) 2003-01-15 EP disclosed
US-6486264-B1 Process for producing hydrogenated ring-opening polymerization polymer of cycloolefin ZEON CORPORATION (JP) 2002-11-26 US disclosed
WO-2002076613-A1 HIGH ACTIVITY METAL CARBENE METATHESIS CATALYSTS GENERATED USING A THERMALLY ACTIVATED N-HETEROCYCLIC CARBENE PRECURSOR CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2002-10-03 WO disclosed
EP-1197509-A1 PROCESS FOR PRODUCING HYDROGENATED RING-OPENING POLYMERIZATION POLYMER OF CYCLOOLEFIN Nippon Zeon Co., Ltd. (JP) 2002-04-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10211401-B2 Organic semiconductor material TST, TH, TPR SIGMAR1 111/4885MEN1 1089/4885KMT2A 1629/4885
US-20030144437-A1 High activity metal carbene metathesis catalysts generated using a thermally activated N-heterocyclic carbene precursor NQO1, NIT2, ALOX5 SIGMAR1 2476/4885MEN1 1386/4885KMT2A 2684/4885
US-20170069845-A1 ORGANIC SEMICONDUCTOR MATERIAL TST, TH, TPR SIGMAR1 111/4885MEN1 1089/4885KMT2A 1629/4885
US-20030083445-A1 High activity metal carbene metathesis catalysts generated using a thermally activated N-heterocyclic carbene precursor NQO1, NIT2, ALOX5 SIGMAR1 2476/4885MEN1 1386/4885KMT2A 2684/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.