Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6102273 | 0.86 | MAPT (0.39) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL6099928 | 0.86 | THRB (0.42) | KDM4ECASP3ALDH1A1HPGDMAPT | |
| SCHEMBL6100789 | 0.80 | CMA1 (0.53) | CMA1KDM4EGSK3AGSK3BCASP3 | |
| SCHEMBL6102021 | 0.77 | TSHR (0.41) | KDM4EALDH1A1HPGDHTTMAPT | |
| SCHEMBL6102010 | 0.77 | UBE2N (0.42) | KDM4EALDH1A1HPGDHTTMEN1 | |
| SCHEMBL5766269 | 0.74 | ALDH1A1 (0.42) | KDM4EGSK3AGSK3BCASP3ALDH1A1 | |
| SCHEMBL4689945 | 0.72 | CASP3 (0.40) | CASP3HPGDRAB9AHTTMAPT | |
| SCHEMBL14260614 | 0.72 | KDM4E (0.42) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL2288506 | 0.71 | CASP3 (0.39) | CASP3ALDH1A1HPGD | |
| SCHEMBL2643216 | 0.70 | CMA1 (0.70) | CMA1KDM4EGSK3AGSK3BCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060211724-A1 | Hiv integrase inhibitors | VERSCHUEREN GASTON W | 2006-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211724-A1 | Hiv integrase inhibitors | SULT1A1, SULT2A1, SULT1E1 | CMA1 2557/4885KDM4E 4133/4885GSK3A 2444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.