Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 2/20 | 0.41 |
| ▸ | APAF1 | O14727 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.35 |
| ▸ | UCHL3 | P15374 | 2/20 | 0.35 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6101728 | 0.99 | CDC25B (0.39) | CDC25BAPAF1MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL5806753 | 0.95 | CDC25B (0.38) | CDC25BAPAF1MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL5794020 | 0.94 | CDC25B (0.37) | CDC25BAPAF1MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL6099553 | 0.84 | ABCB11 (0.43) | APAF1MAPTSMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL5820682 | 0.83 | HPGD (0.45) | MAPTSMN1; SMN2KMT2ATSHR | |
| SCHEMBL6101454 | 0.79 | HPGD (0.42) | MAPTSMN1; SMN2KMT2ATSHRTDP1 | |
| SCHEMBL5808490 | 0.78 | ALDH1A1 (0.44) | APAF1MAPTSMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL5810421 | 0.77 | APAF1 (0.37) | APAF1MAPTSMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL5767183 | 0.73 | KMT2A (0.46) | APAF1MAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4210485 | 0.68 | ALDH1A1 (0.55) | MAPTSMN1; SMN2KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060211724-A1 | Hiv integrase inhibitors | VERSCHUEREN GASTON W | 2006-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211724-A1 | Hiv integrase inhibitors | SULT1A1, SULT2A1, SULT1E1 | CDC25B 3190/4885APAF1 4635/4885MAPT 4622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.