Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 3/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4206481 | 0.83 | SIGMAR1 (0.46) | MEN1KMT2ACNR2CNR1LMNA | |
| SCHEMBL18429032 | 0.79 | CHRM2 (0.50) | LMNATDP1CHRM2CHRM4CHRM5 | |
| SCHEMBL9690903 | 0.77 | CHRM2 (0.51) | LMNATDP1CHRM2CHRM4CHRM5 | |
| SCHEMBL6630975 | 0.75 | TDP1 (0.43) | MEN1KMT2ALMNASMN1; SMN2TDP1 | |
| SCHEMBL6169050 | 0.75 | ALDH1A1 (0.52) | MEN1KMT2ALMNACHRM2CHRM3 | |
| SCHEMBL3703032 | 0.71 | HTR2A (0.57) | LMNAPKM | |
| SCHEMBL7712884 | 0.70 | AKT1 (0.44) | KMT2AL3MBTL1CHRM2CHRM4CHRM5 | |
| SCHEMBL8459141 | 0.70 | HRH3 (0.51) | CNR2CNR1SIGMAR1TSHRCYP2C19 | |
| Toluene SCHEMBL5404912 | 0.69 | TDP1 (0.53) | MEN1KMT2ACNR2CNR1LMNA | |
| SCHEMBL7545610 | 0.69 | SIGMAR1 (0.52) | MEN1KMT2ASMN1; SMN2L3MBTL1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060194834-A1 | Azacyclic compounds | ACADIA PHARMACEUTICALS, INC. | 2006-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194834-A1 | Azacyclic compounds | HTR6, HTR5A, HNMT | MEN1 710/4885KMT2A 1270/4885CNR2 74/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.