Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29186004 | 0.86 | AKR1C2 (0.44) | TSHRGPR35ALDH1A1TTRDPP4 | |
| SCHEMBL29185997 | 0.85 | ALDH1A1 (0.46) | TSHRGPR35ALDH1A1TTRDPP4 | |
| SCHEMBL3239188 | 0.84 | TSHR (0.46) | TSHRGPR35ALDH1A1GRIN2DGRIN3B | |
| SCHEMBL9132988 | 0.82 | TSHR (0.60) | TSHRGPR35ALDH1A1GRIN2DGRIN3B | |
| SCHEMBL1477313 | 0.81 | ALDH1A1 (0.54) | TSHRALDH1A1DPP4CA1CA2 | |
| SCHEMBL17344236 | 0.81 | ALDH1A1 (0.47) | TSHRALDH1A1CA1CA2CDK2 | |
| SCHEMBL31470133 | 0.80 | SMN1; SMN2 (0.49) | TSHRGPR35ALDH1A1CA1CA2 | |
| SCHEMBL7902778 | 0.80 | SMN1; SMN2 (0.49) | TSHRGPR35ALDH1A1CA1CA2 | |
| SCHEMBL8563644 | 0.80 | TSHR (0.53) | TSHRGPR35ALDH1A1DPP4CA1 | |
| SCHEMBL27739227 | 0.80 | CRHBP (0.43) | ALDH1A1DPP4CDK2AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117586126-A | Synthesis method of 4, 6-dichloro-3-hydroxy-2-nitrobenzoic acid | 扬州市荣晶新材料科技有限公司 | 2024-02-23 | — | — | CN | claimed |
| CN-117586126-A | Synthesis method of 4, 6-dichloro-3-hydroxy-2-nitrobenzoic acid | 扬州市荣晶新材料科技有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-117586126-A | Synthesis method of 4, 6-dichloro-3-hydroxy-2-nitrobenzoic acid | 扬州市荣晶新材料科技有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-117586126-A | Synthesis method of 4, 6-dichloro-3-hydroxy-2-nitrobenzoic acid | 扬州市荣晶新材料科技有限公司 | 2024-02-23 | — | — | CN | disclosed |
| EP-2379510-B1 | QUINAZOLINONE COMPOUNDS | PRANA BIOTECHNOLOGY LTD (AU) | 2016-10-26 | — | — | EP | disclosed |
| EP-2379510-B1 | QUINAZOLINONE COMPOUNDS | PRANA BIOTECHNOLOGY LTD (AU) | 2016-10-26 | — | — | EP | disclosed |
| US-20150359796-A1 | QUINAZOLINONE COMPOUNDS | PRANA BIOTECHNOLOGY LIMITED (AU) | 2015-12-17 | — | — | US | disclosed |
| US-20150359796-A1 | QUINAZOLINONE COMPOUNDS | PRANA BIOTECHNOLOGY LIMITED (AU) | 2015-12-17 | — | — | US | disclosed |
| US-20150359796-A1 | QUINAZOLINONE COMPOUNDS | PRANA BIOTECHNOLOGY LIMITED (AU) | 2015-12-17 | — | — | US | disclosed |
| US-9145375-B2 | Quinazolinone compounds | PRANA BIOTECHNOLOGY LIMITED (AU) | 2015-09-29 | — | — | US | disclosed |
| US-20080119470-A1 | Neurologically-Active Compounds | XOMA TECHNOLOGY LTD. | 2008-05-22 | — | — | US | disclosed |
| US-20060167000-A1 | Neurologically-active compounds | PRANA BIOTECHNOLOGY LIMITED (AU) | 2006-07-27 | — | — | US | disclosed |
| WO-2005095360-A1 | NEUROLOGICALLY-ACTIVE COMPOUNDS | PRANA BIOTECHNOLOGY LIMITED (AU) | 2005-10-13 | — | — | WO | disclosed |
| EP-1558585-A1 | NEUROLOGICALLY-ACTIVE COMPOUNDS | Prana Biotechnology Ltd (AU) | 2005-08-03 | — | — | EP | disclosed |
| WO-2004031161-A1 | NEUROLOGICALLY-ACTIVE COMPOUNDS | PRANA BIOTECHNOLOGY LIMITED (AU) | 2004-04-15 | — | — | WO | disclosed |
| EP-0686145-B1 | NEW COMPOUNDS | UNIV MARYLAND (US) | 2000-01-26 | — | — | EP | disclosed |
| US-5883129-A | Hydroxylated anthranilic acid derivatives | ASTRA AKTIEBOLAG (SE) | 1999-03-16 | — | — | US | disclosed |
| US-5523475-A | New compounds | AKTIEBOLAGET ASTRA (SE) | 1996-06-04 | — | — | US | disclosed |
| EP-0686145-A1 | NEW COMPOUNDS | AKTIEBOLAGET ASTRA (SE) | 1995-12-13 | — | — | EP | disclosed |
| WO-1994019316-A1 | NEW COMPOUNDS | AKTIEBOLAGET ASTRA (SE) | 1994-09-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150359796-A1 | QUINAZOLINONE COMPOUNDS | PARK7, SNCA, NDUFV2 | TSHR 3537/4885GPR35 1836/4885ALDH1A1 866/4885 |
| US-20080119470-A1 | Neurologically-Active Compounds | ACHE, PSEN1, PSEN2 | TSHR 4660/4885GPR35 1767/4885ALDH1A1 1120/4885 |
| US-20060167000-A1 | Neurologically-active compounds | ACHE, PSEN1, PSEN2 | TSHR 4668/4885GPR35 2744/4885ALDH1A1 634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.