Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 4/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | PRKCI | P41743 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6112997 | 1.00 | ACHE (0.53) | ACHEEGFRMAOAMAOBPRKCI | |
| SCHEMBL9521410 | 0.96 | ACHE (0.53) | ACHEEGFRMAOAMAOBPRKCI | |
| SCHEMBL1535917 | 0.88 | ACHE (0.56) | ACHEEGFRMAOAMAOBPRKCI | |
| SCHEMBL29600536 | 0.81 | MAOA (0.47) | MAOAMAOBPRKCIHSD17B1KDM4E | |
| SCHEMBL19132606 | 0.81 | HSD17B1 (0.41) | ACHEMAOAMAOBPRKCIPSMB5 | |
| SCHEMBL24362726 | 0.81 | MAOA (0.47) | MAOAMAOBPRKCIHSD17B1KDM4E | |
| SCHEMBL24362691 | 0.81 | MAOA (0.44) | ACHEMAOAMAOBPRKCIPSMB5 | |
| SCHEMBL9827612 | 0.79 | PSMB5 (0.41) | ACHEEGFRMAOAMAOBPRKCI | |
| SCHEMBL23783031 | 0.77 | MAOA (0.44) | ACHEMAOAMAOBPRKCIHSD17B1 | |
| SCHEMBL3987533 | 0.77 | MAOA (0.44) | ACHEMAOAMAOBPRKCIPSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120130129-A1 | Efficient Method for Preparing Functionalized Benzosuberenes | BAYLOR UNIVERSITY (US) | 2012-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120130129-A1 | Efficient Method for Preparing Functionalized Benzosuberenes | CYP2B6, CYP2A6, GABRA6 | ACHE 3337/4885EGFR 545/4885MAOA 496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.