Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9820844 | 0.90 | TGFBR1 (0.33) | TGFBR1 | |
| SCHEMBL16343142 | 0.88 | BBOX1 (0.41) | — | |
| SCHEMBL969702 | 0.88 | BBOX1 (0.37) | — | |
| SCHEMBL1563365 | 0.87 | CHRM2 (0.36) | TGFBR1 | |
| SCHEMBL153023 | 0.86 | POLB (0.37) | — | |
| Hydrochloric Acid SCHEMBL475592 | 0.85 | CHRM2 (0.35) | TGFBR1 | |
| SCHEMBL19971333 | 0.83 | BBOX1 (0.41) | TGFBR1 | |
| SCHEMBL6117144 | 0.82 | BBOX1 (0.36) | — | |
| SCHEMBL6118217 | 0.82 | POLB (0.36) | — | |
| Hydrochloric Acid SCHEMBL6117337 | 0.81 | DNM1 (0.36) | TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722824-B2 | Relative permeability modifiers based on hydrophobically modified cationic copolymers | ENI S.P.A. (IT) | 2014-05-13 | — | — | US | disclosed |
| US-20120130037-A1 | RELATIVE PERMEABILITY MODIFIERS BASED ON HYDROPHOBICALLY MODIFIED CATIONIC COPOLYMERS | ENI S.P.A. (IT) | 2012-05-24 | — | — | US | disclosed |