Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.35 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.35 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1563365 | 0.98 | CHRM2 (0.36) | CHRM2CYP2D6CHRM1ADRA2CCHRM3 | |
| Hydrochloric Acid SCHEMBL6117337 | 0.95 | DNM1 (0.36) | CHRM2CYP2D6CHRM1ADRA2CCHRM3 | |
| Bromide SCHEMBL23607564 | 0.90 | DNM1 (0.42) | DNM1KDM4EMAPK1HIF1AMEN1 | |
| Hydrochloric Acid SCHEMBL475743 | 0.89 | CHRM2 (0.43) | CHRM2CYP2D6CHRM1ADRA2CCHRM3 | |
| SCHEMBL9820844 | 0.89 | TGFBR1 (0.33) | CHRM2CYP2D6CHRM1ADRA2CCHRM3 | |
| SCHEMBL7056776 | 0.87 | CHRM2 (0.44) | CHRM2CYP2D6CHRM1ADRA2CCHRM3 | |
| Hydrochloric Acid SCHEMBL5399324 | 0.86 | TGFBR1 (0.37) | TGFBR1KDM4EMAPK1HIF1AALDH1A1 | |
| Bromide SCHEMBL6116969 | 0.85 | CHRM2 (0.43) | CHRM2CYP2D6CHRM1ADRA2CCHRM3 | |
| SCHEMBL6117441 | 0.85 | TGFBR1 (0.30) | TGFBR1 | |
| SCHEMBL15253793 | 0.84 | EPHX1 (0.46) | HIF1AEPHX1PLA2G2AALDH1A1PLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 330 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11166904-B2 | Cosmetic compositions containing oxazoline functionalized polymers and carboxyl group-containing polymers | L'OREAL (FR) | 2021-11-09 | — | — | US | claimed |
| US-20200069557-A1 | COSMETIC COMPOSITIONS CONTAINING OXAZOLINE FUNCTIONALIZED POLYMERS AND CARBOXYL GROUP-CONTAINING POLYMERS | L'OREAL (FR) | 2020-03-05 | — | — | US | claimed |
| US-20170189307-A1 | COMPOSITIONS AND METHODS FOR TREATING KERATINOUS SUBSTRATES | L'OREAL (FR) | 2017-07-06 | — | — | US | claimed |
| US-20110230619-A1 | Nitrogen-Containing Organosilicon Graft Copolymers | EVONIK GOLDSCHMIDT GMBH (DE) | 2011-09-22 | — | — | US | claimed |
| EP-1188571-B1 | Ink-jet printing method | MEADWESTVACO CORP (US) | 2005-05-11 | — | — | EP | claimed |
| EP-1188571-A1 | Ink-jet printing method | WESTVACO CORPORATION (US) | 2002-03-20 | — | — | EP | claimed |
| US-4171418-A | WATER-SOLUBLR ACRYLAMIDE COPOLYMERS CONTAINING HYDROPHOBIC AND IONIC UNITS | AMERICAN CYANAMID COMPANY (US) | 1979-10-16 | — | — | US | claimed |
| CN-119654132-A | Composition for treating keratin fibres | 莱雅公司 | 2025-03-18 | — | — | CN | disclosed |
| US-12195668-B2 | Coupling agent to enhanced coupling of optical fibers deployed in subsurface wells | HALLIBURTON ENERGY SERVICES, INC. (US) | 2025-01-14 | — | — | US | disclosed |
| WO-2024237914-A1 | A COUPLING AGENT TO ENHANCED COUPLING OF OPTICAL FIBERS DEPLOYED IN SUBSURFACE WELLS | HALLIBURTON ENERGY SERVICES, INC. (US) | 2024-11-21 | — | — | WO | disclosed |
| US-20240384155-A1 | COUPLING AGENT TO ENHANCED COUPLING OF OPTICAL FIBERS DEPLOYED IN SUBSURFACE WELLS | HALLIBURTON ENERGY SERVICES, INC. | 2024-11-21 | — | — | US | disclosed |
| WO-2024031596-A1 | COMPOSITION FOR TREATING KERATIN FIBERS | L'OREAL (FR) | 2024-02-15 | — | — | WO | disclosed |
| US-11166904-B2 | Cosmetic compositions containing oxazoline functionalized polymers and carboxyl group-containing polymers | L'OREAL (FR) | 2021-11-09 | — | — | US | disclosed |
| EP-1130215-A2 | Stimulating fluid production from unconsolidated formations | Halliburton Energy Services, Inc. (US) | 2001-09-05 | — | — | EP | disclosed |
| US-6257335-B1 | Stimulating fluid production from unconsolidated formations | HALLIBURTON ENERGY SERVICES, INC. | 2001-07-10 | — | — | US | disclosed |
| EP-0627324-B1 | Ink jet recording medium | MITSUBISHI PAPER MILLS LTD (JP) | 1997-01-02 | — | — | EP | disclosed |
| US-5439739-A | Support having ink receiving layer containing crosslinked water soluble polymer with repeating units derived from quaternary ammonium salts, amines, acids and amides; water resistance | MITSUBISHI PAPER MILLS LIMITED (JP) | 1995-08-08 | — | — | US | disclosed |
| EP-0627324-A1 | Ink jet recording medium | MITSUBISHI PAPER MILLS, LTD. (JP) | 1994-12-07 | — | — | EP | disclosed |
| US-5362827-A | Free radical addition polymerization of polymers for treatment of water | EXXON RESEARCH & ENGINEERING CO. (US) | 1994-11-08 | — | — | US | disclosed |
| US-4171418-A | WATER-SOLUBLR ACRYLAMIDE COPOLYMERS CONTAINING HYDROPHOBIC AND IONIC UNITS | AMERICAN CYANAMID COMPANY (US) | 1979-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11166904-B2 | Cosmetic compositions containing oxazoline functionalized polymers and carboxyl group-containing polymers | KRT18, CUTA, HDAC7 | CHRM2 2929/4885CHRM1 2263/4885CHRM3 1704/4885 |
| US-20200069557-A1 | COSMETIC COMPOSITIONS CONTAINING OXAZOLINE FUNCTIONALIZED POLYMERS AND CARBOXYL GROUP-CONTAINING POLYMERS | KRT18, CUTA, HDAC7 | CHRM2 2929/4885CHRM1 2263/4885CHRM3 1704/4885 |
| US-20170189307-A1 | COMPOSITIONS AND METHODS FOR TREATING KERATINOUS SUBSTRATES | KRT18, PRKDC, PLOD3 | CHRM2 3314/4885CHRM1 3059/4885CHRM3 3704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.