SCHEMBL6121990

SCHEMBL6121990

CCCC(=O)C(O)Cc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.47
SLC15A1 P46059 1/20 0.46
TRPA1 O75762 2/20 0.46
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
ALPI P09923 1/20 0.44
PKM P14618 1/20 0.44
PTGS1 P23219 1/20 0.44
XIAP P98170 1/20 0.44
SLC7A5 Q01650 1/20 0.44
KEAP1 Q14145 1/20 0.44
LTA4H P09960 1/20 0.44
ALPL P05186 1/20 0.43
POLB P06746 1/20 0.43
ALPG P10696 1/20 0.43
CPA3 P15088 1/20 0.43
MDM2 Q00987 1/20 0.43
UBE2N P61088 1/20 0.43
CES2 O00748 1/20 0.43
CES1 P23141 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7104035 0.86 EPHX2 (0.53) CES2CES1
SCHEMBL28180885 0.85 TPMT (0.42) SLC15A1POLBMDM2CES2CES1
SCHEMBL8919717 0.85 CYP1A2 (0.50) CYP1A2SLC15A1TRPA1NPC1RAB9A
SCHEMBL8380411 0.85 CYP1A2 (0.50) CYP1A2SLC15A1TRPA1NPC1RAB9A
SCHEMBL109575 0.85 CYP1A2 (0.50) CYP1A2SLC15A1TRPA1NPC1RAB9A
SCHEMBL2148366 0.84 SLC6A2 (0.49) SLC7A5
SCHEMBL476969 0.83 KEAP1 (0.61) CYP1A2SLC15A1TRPA1ALPIPKM
SCHEMBL12950490 0.82 ALDH1A1 (0.47) CYP1A2TRPA1KEAP1
Butyric Acid SCHEMBL10490423 0.82 CPA3 (0.53) CYP1A2SLC15A1TRPA1ALPIPKM
SCHEMBL2565008 0.81 CYP1A2 (0.52) CYP1A2SLC15A1NPC1RAB9AALPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2872642-A1 PROCESS FOR USING TOBACCO Kind Consumer Limited (GB) 2015-05-20 EP disclosed
WO-2014009749-A1 PROCESS FOR USING TOBACCO KIND CONSUMER LIMITED (GB) 2014-01-16 WO disclosed
WO-2012068310-A2 COMPOSITIONS AND METHODS FOR IMPROVED SACCHARIFICATION OF GENETICALLY MODIFIED PLANT-DERIVED BIOMASS QTEROS, INC. (US) 2012-05-24 WO disclosed
WO-2000023608-A1 PREPARATION OF AMINO ALCOHOLS DSM BIOTECH GMBH (DE) 2000-04-27 WO disclosed