SCHEMBL616009

SCHEMBL616009

CC=[Zr](c1ccccc1)(c1ccccc1)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 6/20 0.32
KDM4E B2RXH2 2/20 0.32
HTR2A P28223 2/20 0.32
LMNA P02545 1/20 0.32
TP53 P04637 1/20 0.32
CHRM2 P08172 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CHRM1 P11229 1/20 0.32
DRD2 P14416 1/20 0.32
ADRA2B P18089 1/20 0.32
ADRA2C P18825 1/20 0.32
NFKB1 P19838 1/20 0.32
CHRM3 P20309 1/20 0.32
SLC6A2 P23975 1/20 0.32
HTR2C P28335 1/20 0.32
ADRA1A P35348 1/20 0.32
HRH1 P35367 1/20 0.32
DRD3 P35462 1/20 0.32
THPO P40225 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9066450 0.81 HTR6 (0.33) SIGMAR1HTR6
SCHEMBL3385263 0.79 HTR2A (0.34) SIGMAR1HTR2AHTR6
SCHEMBL61249 0.79 HTR2A (0.34) SIGMAR1KDM4EHTR2ALMNATP53
SCHEMBL7061981 0.77 SIGMAR1 (0.34) SIGMAR1KDM4EHTR2ALMNATP53
SCHEMBL3385445 0.77 HTR6 (0.33) SIGMAR1HTR2AHTR6
Hydrochloric Acid SCHEMBL7065674 0.76 SIGMAR1 (0.33) SIGMAR1KDM4EHTR2ALMNATP53
SCHEMBL616106 0.76 HTR6 (0.33) SIGMAR1KDM4EHTR2ALMNATP53
SCHEMBL61106 0.76 HTR6 (0.33) SIGMAR1KDM4EHTR2ALMNATP53
SCHEMBL7066166 0.76 SIGMAR1 (0.33) SIGMAR1KDM4EHTR2ALMNATP53
SCHEMBL1130930 0.76 HTR6 (0.33) SIGMAR1KDM4EHTR2ALMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 337 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3480258-B1 SOLID MAO COMPOSITION CONTAINING AL2O3 AND METHOD FOR PRODUCING SAME TOSOH FINECHEM CORP (JP) 2023-12-20 EP disclosed
US-20230137384-A1 ARTICLE OF MANUFACTURE COMPRISING LOCAL ANESTHETIC, BUFFER, AND GLYCOSAMINOGLYCAN IN SYRINGE WITH IMPROVED STABILITY URIGEN PHARMACEUTICALS, INC. 2023-05-04 US disclosed
EP-3893054-A1 PATTERN FORMING METHOD, PHOTOSENSITIVE RESIN COMPOSITION, CURED FILM, LAMINATE, AND DEVICE FUJIFILM Corporation (JP) 2021-10-13 EP disclosed
EP-3893053-A1 PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMING METHOD, CURED FILM, MULTILAYER BODY AND DEVICE FUJIFILM Corporation (JP) 2021-10-13 EP disclosed
US-20210302835-A1 PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMING METHOD, CURED FILM, LAMINATE, AND DEVICE FUJIFILM CORPORATION (JP) 2021-09-30 US disclosed
US-20210302836-A1 PATTERN FORMING METHOD, PHOTOSENSITIVE RESIN COMPOSITION, CURED FILM, LAMINATE, AND DEVICE FUJIFILM CORPORATION (JP) 2021-09-30 US disclosed
US-20210283172-A1 ARTICLE OF MANUFACTURE COMPRISING LOCAL ANESTHETIC, BUFFER, AND GLYCOSAMINOGLYCAN IN SYRINGE WITH IMPROVED STABILITY URIGEN PHARMACEUTICALS, INC. 2021-09-16 US disclosed
US-10870715-B2 Solid polyaluminoxane composition, olefin polymerization catalyst, olefin polymer production method and solid polyaluminoxane composition production method MITSUI CHEMICALS, INC. (JP) 2020-12-22 US disclosed
EP-3492982-B1 PHOTOSENSITIVE RESIN COMPOSITION, CURED FILM, LAMINATE, METHOD FOR PRODUCING CURED FILM, METHOD FOR PRODUCING LAMINATE, AND SEMICONDUCTOR DEVICE FUJIFILM CORP (JP) 2020-11-11 EP disclosed
US-10730969-B2 Solid MAO composition containing Al2O3 and method for producing same TOSOH FINECHEM CORPORATION (JP) 2020-08-04 US disclosed
US-4874734-A USING SOLUTION OF ALUMINOXANE, PARTICULATE CARRIER WITH TRANSITION METAL COMPOUND, SOLVENT IN WHICH ALUMINOXANE IS INSOLUBLE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-10-17 US disclosed
EP-0327649-A1 CATALYST FOR OLEFIN POLYMERIZATION AND PROCESS FOR ITS PREPARATION MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-08-16 EP disclosed
EP-0328348-A2 Olefin polymerization catalyst and process for the polymerization of olefins MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-08-16 EP disclosed
EP-0324856-A1 PROCESS FOR POLYMERIZING OLEFIN MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-07-26 EP disclosed
EP-0314797-A1 OLEFIN POLYMERIZATION CATALYST AND PROCESS FOR POLYMERIZING OLEFIN MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-05-10 EP disclosed
EP-0295312-A1 SOLID CATALYST FOR OLEFIN POLYMERIZATION AND PROCESS FOR ITS PREPARATION MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-12-21 EP disclosed
EP-0294942-A1 Solid catalyst for polymerizing an olefin MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-12-14 EP disclosed
EP-0285443-A1 Process for producing solid catalyst for polymerization of olefins MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-10-05 EP disclosed
EP-0283164-A2 Cyclo-olefinic random copolymer, olefinic random copolymer, and process for producing cyclo-olefinic random copolymers MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-09-21 EP disclosed
EP-0279586-A2 Finely divided aluminoxane, process for producing same and its use MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-08-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210283172-A1 ARTICLE OF MANUFACTURE COMPRISING LOCAL ANESTHETIC, BUFFER, AND GLYCOSAMINOGLYCAN IN SYRINGE WITH IMPROVED STABILITY OGFR, ALOX5, PTGS1 SIGMAR1 151/4885KDM4E 4109/4885HTR2A 2553/4885
US-20230137384-A1 ARTICLE OF MANUFACTURE COMPRISING LOCAL ANESTHETIC, BUFFER, AND GLYCOSAMINOGLYCAN IN SYRINGE WITH IMPROVED STABILITY OGFR, ALOX5, PTGS1 SIGMAR1 151/4885KDM4E 4109/4885HTR2A 2553/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.