Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CCL2 | P13500 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL61249 | 0.79 | HTR2A (0.34) | HTR2ASIGMAR1KDM4EBRD4CCL2 | |
| SCHEMBL1130930 | 0.76 | HTR6 (0.33) | HTR2ASIGMAR1KDM4EBRD4CCL2 | |
| SCHEMBL61106 | 0.76 | HTR6 (0.33) | HTR2ASIGMAR1KDM4EBRD4CCL2 | |
| SCHEMBL616106 | 0.76 | HTR6 (0.33) | HTR2ASIGMAR1KDM4EBRD4CCL2 | |
| SCHEMBL7525478 | 0.75 | HTR6 (0.32) | HTR2ASIGMAR1HTR6 | |
| SCHEMBL7644875 | 0.74 | P2RX1 (0.31) | BRD4CCL2MEN1KMT2A | |
| SCHEMBL6918052 | 0.73 | HTR6 (0.31) | HTR2AHTR6 | |
| SCHEMBL819261 | 0.73 | HTR2A (0.34) | HTR2ASIGMAR1KDM4ELMNATP53 | |
| SCHEMBL616009 | 0.73 | SIGMAR1 (0.32) | HTR2ASIGMAR1KDM4ELMNATP53 | |
| SCHEMBL6917307 | 0.73 | HTR2A (0.32) | HTR2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0448115-B1 | Method for producing a polyolefin | TOSOH CORP (JP) | 1998-01-07 | — | — | EP | disclosed |
| US-5629390-A | Method for producing a polyolefin | TOSOH CORPORATION (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0448115-A2 | Method for producing a polyolefin | Tosoh Corporation (JP) | 1991-09-25 | — | — | EP | disclosed |