SCHEMBL6128191

SCHEMBL6128191

Cn1nc(S(=O)(=O)C(F)F)c(C(=O)Cl)c1F

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL439648 0.73 PTGER4 (0.33)
SCHEMBL221831 0.71 KDM4E (0.42)
SCHEMBL406709 0.70 MIF (0.33)
SCHEMBL5092253 0.67 SMN1; SMN2 (0.46)
SCHEMBL15237109 0.61 PTGER4 (0.33)
SCHEMBL437422 0.61 PTGER4 (0.37)
SCHEMBL434677 0.61 PTGER4 (0.33)
SCHEMBL13723232 0.60 PTGER4 (0.34) CA1CA2CA9
SCHEMBL440487 0.60 L3MBTL1 (0.36)
SCHEMBL31539136 0.59 PTGER4 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2640707-A1 5-HALOGENOPYRAZOLECARBOXAMIDES Bayer Intellectual Property GmbH (DE) 2013-09-25 EP disclosed
EP-2640191-A1 5-HALOGENOPYRAZOLE(THIO)CARBOXAMIDES Bayer Intellectual Property GmbH (DE) 2013-09-25 EP disclosed
WO-2012065945-A1 5-HALOGENOPYRAZOLE(THIO)CARBOXAMIDES BAYER CROPSCIENCE AG (DE) 2012-05-24 WO disclosed
WO-2012065947-A1 5-HALOGENOPYRAZOLECARBOXAMIDES BAYER CROPSCIENCE AG (DE) 2012-05-24 WO disclosed