Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL437373 | 0.86 | L3MBTL1 (0.40) | L3MBTL1KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL14960654 | 0.86 | ALDH1A1 (0.37) | L3MBTL1KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL28309097 | 0.84 | L3MBTL1 (0.36) | L3MBTL1KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL405756 | 0.84 | L3MBTL1 (0.37) | L3MBTL1KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL16586280 | 0.84 | L3MBTL1 (0.37) | L3MBTL1KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL439648 | 0.82 | PTGER4 (0.33) | PTGER4 | |
| SCHEMBL31539136 | 0.81 | PTGER4 (0.30) | PTGER4 | |
| SCHEMBL16344553 | 0.80 | L3MBTL1 (0.33) | L3MBTL1KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL18396688 | 0.78 | L3MBTL1 (0.38) | L3MBTL1KMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL1357725 | 0.78 | KMT2A (0.39) | L3MBTL1KMT2AALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119954721-A | Pyrazole amide derivative, preparation method and application thereof | 山东省联合农药工业有限公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-110804019-B | Amide compound and preparation method and application thereof | 上海晓明检测技术服务有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-107531640-B | Method for producing 5-fluoro-1H-pyrazole-4-carbonyl fluoride | 拜耳作物科学股份公司 | 2020-10-27 | — | — | CN | disclosed |
| CN-110804019-A | Amide compound and preparation method and application thereof | 上海泰禾国际贸易有限公司 | 2020-02-18 | — | — | CN | disclosed |
| US-20200045965-A1 | METHOD FOR THE CONTROL OF PLANT BACTERIAL DISEASES USING CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-02-13 | — | — | US | disclosed |
| US-10315998-B2 | Amide compound and the preparation method and use thereof | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2019-06-11 | — | — | US | disclosed |
| EP-3000809-B1 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATIVES | BAYER IP GMBH (DE) | 2018-10-31 | — | — | EP | disclosed |
| US-20180206498-A1 | SUBSTITUTED HETEROARYL CARBOXYLIC ACID HYDRAZIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-07-26 | — | — | US | disclosed |
| WO-2018109062-A1 | METHOD FOR THE CONTROL OF PLANT BACTERIAL DISEASES USING CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-06-21 | — | — | WO | disclosed |
| EP-3325467-A1 | SUBSTITUTED HETEROARYL CARBOXYLIC ACID HYDRAZIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS | Bayer CropScience Aktiengesellschaft (DE) | 2018-05-30 | — | — | EP | disclosed |
| WO-2012052491-A2 | 1-(HETEROCYCLIC CARBONYL)-2-SUBSTITUTED PYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2012-04-26 | — | — | WO | disclosed |
| WO-2012052490-A1 | N-BENZYL HETEROCYCLIC CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2012-04-26 | — | — | WO | disclosed |
| EP-2430000-A2 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATIVES | Bayer CropScience Aktiengesellschaft (DE) | 2012-03-21 | — | — | EP | disclosed |
| US-20120065164-A1 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2012-03-15 | — | — | US | disclosed |
| WO-2011151369-A1 | N-[(HET)ARYLETHYL)] PYRAZOLE(THIO)CARBOXAMIDES AND THEIR HETEROSUBSTITUTED ANALOGUES | BAYER CROPSCIENCE AG (DE) | 2011-12-08 | — | — | WO | disclosed |
| WO-2011151370-A1 | N-[(HET)ARYLALKYL)] PYRAZOLE (THIO)CARBOXAMIDES AND THEIR HETEROSUBSTITUTED ANALOGUES | BAYER CROPSCIENCE AG (DE) | 2011-12-08 | — | — | WO | disclosed |
| WO-2011151383-A1 | O-CYCLOPROPYLCYCLOHEXYL-CARBOXANILIDES AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-12-08 | — | — | WO | disclosed |
| US-20110288305-A1 | Process for the preparation of 5-Fluoro-1-alkyl-3-fluoroalkyl-1H-pyrazole-4-carbonyl Chlorides and Fluorides | BAYER CROPSCIENCE AG (DE) | 2011-11-24 | — | — | US | disclosed |
| WO-2010130767-A2 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-11-18 | — | — | WO | disclosed |
| EP-2251331-A1 | Fungicide pyrazole carboxamides derivatives | Bayer CropScience AG (DE) | 2010-11-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10315998-B2 | Amide compound and the preparation method and use thereof | CYP51A1, ERG28, NAT1 | L3MBTL1 4387/4885KMT2A 1139/4885ALDH1A1 692/4885 |
| US-20110288305-A1 | Process for the preparation of 5-Fluoro-1-alkyl-3-fluoroalkyl-1H-pyrazole-4-carbonyl Chlorides and Fluorides | AFF4, AFF1, FLI1 | L3MBTL1 3820/4885KMT2A 910/4885ALDH1A1 398/4885 |
| US-20180206498-A1 | SUBSTITUTED HETEROARYL CARBOXYLIC ACID HYDRAZIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS | GRHPR, HACL2, PAH | L3MBTL1 2851/4885KMT2A 1255/4885ALDH1A1 396/4885 |
| US-20200045965-A1 | METHOD FOR THE CONTROL OF PLANT BACTERIAL DISEASES USING CARBOXAMIDE DERIVATIVES | BROX, NAAA, SIRT5 | L3MBTL1 1328/4885KMT2A 665/4885ALDH1A1 3667/4885 |
| US-20120065164-A1 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATES | CASP5, CTRL, CBR3 | L3MBTL1 1962/4885KMT2A 1498/4885ALDH1A1 4241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.