Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28091168 | 0.83 | GAA (0.49) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL10629487 | 0.80 | KMT2A (0.51) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL3685129 | 0.79 | IDO1 (0.53) | LMNAIDO1GAAKMT2AMEN1 | |
| SCHEMBL10037099 | 0.78 | RAPGEF4 (0.52) | LMNAGAAKMT2AMEN1TDP1 | |
| SCHEMBL11406295 | 0.76 | TRPA1 (0.54) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL3233888 | 0.76 | TRPA1 (0.54) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL30671520 | 0.76 | TRPA1 (0.54) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL7855939 | 0.75 | CRHR1 (0.38) | LMNAIDO1GAAKMT2AMEN1 | |
| SCHEMBL3634659 | 0.75 | TDP1 (0.48) | IDO1GAATDP1ALDH1A1KDM4E | |
| SCHEMBL29714905 | 0.75 | RAB9A (0.44) | LMNAGAAKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6916346-B2 | Primary intermediates for oxidative coloration of hair | THE PROCTER & GAMBLE COMPANY (US) | 2005-07-12 | — | — | US | disclosed |
| EP-1353639-A4 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P & G CLAIROL INC (US) | 2005-01-26 | — | — | EP | disclosed |
| US-20040205908-A1 | Primary intermediates for oxidative coloration of hair | THE PROCTER & GAMBLE COMPANY | 2004-10-21 | — | — | US | disclosed |
| US-6774244-B2 | 6-(SUBSTITUTED AMINO)-M-CRESOLS AND PREPARATION FROM 6-NITRO-M-CRESOL | THE PROCTER & GAMBLE COMPANY | 2004-08-10 | — | — | US | disclosed |
| CN-1486172-A | Primary intermediates for oxidative dyeing of hair | P&G | 2004-03-31 | — | — | CN | disclosed |
| EP-1353639-A1 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | Clairol Incorporated (US) | 2003-10-22 | — | — | EP | disclosed |
| US-20020170124-A1 | Primary intermediates for oxidative coloration of hair | WELLA OPERATIONS US, LLC | 2002-11-21 | — | — | US | disclosed |
| WO-2002058657-A1 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P&G - CLAIROL, INC. (US) | 2002-08-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020170124-A1 | Primary intermediates for oxidative coloration of hair | CYC1, MT-CO1, MT-CO3 | LMNA 1329/4885TRPA1 949/4885CHRM1 2757/4885 |
| US-20040205908-A1 | Primary intermediates for oxidative coloration of hair | CYC1, MT-CO1, MT-CO3 | LMNA 1329/4885TRPA1 949/4885CHRM1 2757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.