Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 9/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MPI | P34949 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31206983 | 1.00 | GPR84 (0.42) | GPR84MEN1KMT2AKDM4EEGFR | |
| SCHEMBL22229815 | 0.85 | GPR84 (0.37) | GPR84KDM4EEGFRHPGDALDH1A1 | |
| SCHEMBL22229661 | 0.83 | ALOX5 (0.46) | GPR84KDM4EHPGDLMNAALDH1A1 | |
| SCHEMBL30364255 | 0.83 | ALOX5 (0.46) | GPR84KDM4EHPGDLMNAALDH1A1 | |
| SCHEMBL25485149 | 0.82 | ALDH1A1 (0.38) | GPR84KDM4EHPGDALDH1A1NPSR1 | |
| SCHEMBL3922387 | 0.82 | KDM4E (0.51) | GPR84MEN1KMT2AKDM4EHPGD | |
| SCHEMBL22187663 | 0.81 | GPR84 (0.48) | GPR84MEN1KMT2AKDM4EHPGD | |
| SCHEMBL29506852 | 0.81 | GPR84 (0.48) | GPR84MEN1KMT2AKDM4EHPGD | |
| SCHEMBL22229718 | 0.81 | MAPT (0.45) | GPR84MEN1KMT2AKDM4EHPGD | |
| SCHEMBL22229662 | 0.81 | GPR84 (0.33) | GPR84MEN1KMT2AKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1341797-A4 | ORTHO SUBSTITUTED CHIRAL PHOSPHINES AND PHOSPHINITES AND THEIR USE IN ASYMMETRIC CATAYLTIC REACTIONS | PENN STATE RES FOUND (US) | 2005-06-15 | — | — | EP | disclosed |
| US-6855657-B2 | Ortho substituted chiral phosphines and phosphinites and their use in asymmetric catalytic reactions | THE PENN STATE RESEARCH FOUNDATION (US) | 2005-02-15 | — | — | US | disclosed |
| US-20040068126-A1 | Ortho substituted chiral phosphines and phosphinites and their use in asymmetric catalytic reactions | THE PENN STATE RESEARCH FOUNDATION | 2004-04-08 | — | — | US | disclosed |
| EP-1341797-A1 | ORTHO SUBSTITUTED CHIRAL PHOSPHINES AND PHOSPHINITES AND THEIR USE IN ASYMMETRIC CATAYLTIC REACTIONS | THE PENN STATE RESEARCH FOUNDATION (US) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002040491-A1 | ORTHO SUBSTITUTED CHIRAL PHOSPHINES AND PHOSPHINITES AND THEIR USE IN ASYMMETRIC CATAYLTIC REACTIONS | THE PENN STATE RESEARCH FOUNDATION (US) | 2002-05-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040068126-A1 | Ortho substituted chiral phosphines and phosphinites and their use in asymmetric catalytic reactions | BCKDK, PDK3, HCK | GPR84 1195/4885MEN1 1900/4885KMT2A 975/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.