Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK3 | P27361 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 7/20 | 0.38 |
| ▸ | F13A1 | P00488 | 5/20 | 0.38 |
| ▸ | TGM1 | P22735 | 5/20 | 0.38 |
| ▸ | BTK | Q06187 | 6/20 | 0.38 |
| ▸ | JAK3 | P52333 | 2/20 | 0.38 |
| ▸ | TEC | P42680 | 1/20 | 0.38 |
| ▸ | TXK | P42681 | 1/20 | 0.38 |
| ▸ | BMX | P51813 | 1/20 | 0.38 |
| ▸ | ITK | Q08881 | 1/20 | 0.38 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1064807 | 0.82 | KDM4E (0.42) | MAPK3TGM2F13A1TGM1BTK | |
| SCHEMBL27828771 | 0.80 | KDM4E (0.47) | KDM4EALDH1A1MAPTADRA1AADRA1B | |
| SCHEMBL5614479 | 0.76 | ALDH1A1 (0.38) | HPGDKDM4EALDH1A1GLAGAA | |
| SCHEMBL16681024 | 0.76 | THRB (0.39) | HPGDKDM4EALDH1A1GLAGAA | |
| SCHEMBL29352309 | 0.75 | TGM2 (0.46) | MAPK3TGM2F13A1TGM1ALDH1A1 | |
| SCHEMBL1064806 | 0.75 | TGM2 (0.46) | MAPK3TGM2F13A1TGM1ALDH1A1 | |
| SCHEMBL17931860 | 0.74 | TGM2 (0.46) | TGM2BTKJAK3TECTXK | |
| SCHEMBL6542697 | 0.74 | ALDH1A1 (0.46) | HPGDKDM4EALDH1A1GLAGAA | |
| SCHEMBL16096123 | 0.74 | TGM2 (0.47) | TGM2F13A1TGM1BTKJAK3 | |
| SCHEMBL14877164 | 0.72 | RXFP1 (0.48) | KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288282-A1 | Inhibitors of histone deacetylase | METHYLGENE, INC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288282-A1 | Inhibitors of histone deacetylase | HDAC1, HDAC5, HDAC3 | MAPK3 1233/4885TGM2 1652/4885F13A1 3999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.