Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | LDHB | P07195 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11203784 | 0.91 | HTR1A (0.43) | HTTALDH1A1HTR1ADRD2KCNH2 | |
| SCHEMBL9839949 | 0.89 | NOS2 (0.42) | LDHALDHBALDH1A1TAAR1KDM4E | |
| SCHEMBL6547753 | 0.87 | LDHA (0.48) | LDHALDHBALDH1A1DRD2TAAR1 | |
| SCHEMBL1263570 | 0.85 | NOS2 (0.42) | LDHALDHBALDH1A1TAAR1KDM4E | |
| SCHEMBL3000166 | 0.84 | HTR2A (0.44) | HTTALDH1A1HTR1ADRD2KCNH2 | |
| SCHEMBL2049765 | 0.80 | SIGMAR1 (0.44) | HTTHTR1ADRD2KCNH2 | |
| SCHEMBL9656297 | 0.79 | TSHR (0.45) | LDHALDHBHTR1ATAAR1CXCR5 | |
| SCHEMBL2723993 | 0.78 | KCNH2 (0.48) | ALDH1A1KCNH2TAAR1HPGD | |
| SCHEMBL6546789 | 0.78 | HTR1A (0.48) | HTTALDH1A1HTR1ADRD2KCNH2 | |
| SCHEMBL30173449 | 0.78 | TAAR1 (0.58) | ALDH1A1HTR1ADRD2KCNH2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9616064-B2 | Rho kinase inhibitors and methods of use | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2017-04-11 | — | — | US | disclosed |
| US-6869908-B2 | Thermal recording material | FUJI PHOTO FILM CO., LTD. (JP) | 2005-03-22 | — | — | US | disclosed |
| EP-0717098-B1 | A refrigerating machine oil and a fluid composition for use in a refrigerating machine | NIPPON MITSUBISHI OIL CORP (JP) | 2004-01-21 | — | — | EP | disclosed |
| US-20030186808-A1 | Thermal recording material | FUJI PHOTO FILM CO., LTD. | 2003-10-02 | — | — | US | disclosed |
| US-5817251-A | AROMATIC HYDROCARBON LUBRICANT | NIPPON OIL CO., LTD. (JP) | 1998-10-06 | — | — | US | disclosed |
| US-5711895-A | Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group | NIPPON OIL CO., LTD. (JP) | 1998-01-27 | — | — | US | disclosed |
| EP-0717098-A2 | A refrigerating machine oil and a fluid composition for use in a refrigerating machine | NIPPON OIL CO. LTD. (JP) | 1996-06-19 | — | — | EP | disclosed |