SCHEMBL6131350

SCHEMBL6131350

CC(C)(C)c1cc(Nc2ncnc(Nc3cc(C(C)(C)C)c(O)c(C(C)(C)C)c3)n2)cc(C(C)(C)C)c1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
GAA P10253 2/20 0.46
TDP1 Q9NUW8 1/20 0.46
CA2 P00918 3/20 0.44
CA1 P00915 2/20 0.44
POLB P06746 1/20 0.42
TYR P14679 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
ALOX15 P16050 2/20 0.39
MAPT P10636 2/20 0.39
HPN P05981 1/20 0.39
SIRT5 Q9NXA8 1/20 0.39
MEN1 O00255 2/20 0.39
CYP1A2 P05177 2/20 0.39
CYP3A4 P08684 2/20 0.39
TSHR P16473 2/20 0.39
MAPK1 P28482 2/20 0.39
BLM P54132 2/20 0.39
KMT2A Q03164 2/20 0.39
ATM Q13315 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1668655 0.89 ALDH1A1 (0.41) ALDH1A1GAATDP1CA2CA1
SCHEMBL3126822 0.86 ALDH1A1 (0.46) ALDH1A1GAATDP1CA2CA1
SCHEMBL28932206 0.83 GAA (0.34) ALDH1A1GAATDP1CA2CA1
SCHEMBL10869800 0.81 NPC1 (0.46) ALDH1A1GAATDP1CA2CA1
Octane SCHEMBL7523713 0.81 NR5A2 (0.35) ALDH1A1GAATDP1CA2CA1
SCHEMBL9841885 0.81 ALDH1A1 (0.47) ALDH1A1GAATDP1CA2CA1
SCHEMBL9842110 0.80 SYK (0.44) ALDH1A1GAATDP1CA2CA1
SCHEMBL18459329 0.79 CA2 (0.61) ALDH1A1GAATDP1CA2CA1
SCHEMBL11613891 0.78 ALDH1A1 (0.45) ALDH1A1GAATDP1CA2CA1
SCHEMBL10870243 0.78 NFKB1 (0.45) ALDH1A1GAATDP1CA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022080266-A1 NOVEL PHENOLIC COMPOUND AND RESIN COMPOSIION CONTAINING SAID COMPOUND 住友化学株式会社 2022-04-21 WO disclosed
US-20050267248-A1 Method for improving the paint adhesion of compatibilized polyphenylene ether-polyamide compositions CITIBANK, N.A., AS COLLATERAL AGENT 2005-12-01 US disclosed
US-6936652-B2 Method for improving the paint adhesion of compatibilized polyphenylene ether-polyamide compositions GENERAL ELECTRIC COMPANY (US) 2005-08-30 US disclosed
US-20030130406-A1 Method for improving the paint adhesion of compatibilized polyphenylene ether-polyamide compositions CITIBANK, N.A., AS COLLATERAL AGENT 2003-07-10 US disclosed
US-4673700-A Amide substituted benzylhydroxylamines and stabilized polyolefin compositions CIBA-GEIGY CORPORATION (US) 1987-06-16 US disclosed
US-4612393-A Bis(substituted thioalkyl)hydroxylamines and stabilized polyolefin compositions CIBA-GEIGY CORPORATION (US) 1986-09-16 US disclosed