Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HPN | P05981 | 1/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3126822 | 0.84 | ALDH1A1 (0.46) | ALDH1A1GAATDP1CA2CA1 | |
| SCHEMBL10574173 | 0.83 | ALDH1A1 (0.42) | ALDH1A1GAATDP1CA2CA1 | |
| SCHEMBL9842110 | 0.81 | SYK (0.44) | ALDH1A1GAATDP1CA2CA1 | |
| SCHEMBL6131350 | 0.81 | ALDH1A1 (0.46) | ALDH1A1GAATDP1CA2CA1 | |
| SCHEMBL18459329 | 0.80 | CA2 (0.61) | ALDH1A1GAATDP1CA2CA1 | |
| SCHEMBL9841907 | 0.77 | ALDH1A1 (0.42) | ALDH1A1GAATDP1CA2CA1 | |
| SCHEMBL9123037 | 0.77 | ALDH1A1 (0.36) | ALDH1A1GAATDP1LMNAKDM4E | |
| SCHEMBL10870243 | 0.76 | NFKB1 (0.45) | ALDH1A1GAATDP1CA2CA1 | |
| SCHEMBL11613891 | 0.76 | ALDH1A1 (0.45) | ALDH1A1GAATDP1CA2CA1 | |
| SCHEMBL10869800 | 0.76 | NPC1 (0.46) | ALDH1A1GAATDP1CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254259-A2 | p-Aminophenol derivatives | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1988-01-27 | — | — | EP | claimed |
| US-5059598-A | Antiinflammatory agents; lipoxygenase inhibitors; arthritis; asthma | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1991-10-22 | — | — | US | disclosed |
| US-4868183-A | ANTIINFLAMMATORY, ENZYME INHIBITORS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1989-09-19 | — | — | US | disclosed |
| EP-0254259-A2 | p-Aminophenol derivatives | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1988-01-27 | — | — | EP | disclosed |