Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | NEK2 | P51955 | 1/20 | 0.32 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31645774 | 1.00 | MAPT (0.36) | MAPTALDH1A1NSD2EGFRLMNA | |
| SCHEMBL3199976 | 0.71 | ALDH1A1 (0.44) | ALDH1A1LMNATDP1GAATSHR | |
| SCHEMBL2919461 | 0.71 | MAPT (0.52) | MAPTALDH1A1NSD2EGFRLMNA | |
| SCHEMBL28343364 | 0.70 | CRHBP (0.38) | ALDH1A1LMNATSHRKDM4E | |
| SCHEMBL3197827 | 0.70 | TSHR (0.42) | ALDH1A1GAATSHRKDM4E | |
| SCHEMBL17721318 | 0.69 | — | — | |
| SCHEMBL3212320 | 0.69 | GABRA1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL7249040 | 0.69 | — | — | |
| SCHEMBL3211775 | 0.69 | USP1 (0.30) | — | |
| SCHEMBL3686925 | 0.69 | ALDH1A1 (0.35) | ALDH1A1LMNAL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6919412-B1 | Monocyclopentadienyl complexes of chromium, molybdenum or tungsten with a donor bridge | BASELL POLYOLEFINE GMBH (DE) | 2005-07-19 | — | — | US | disclosed |
| US-6838563-B2 | Monocyclopentadienyl complexes of chromium, molybdenum or tungsten | BASELL POLYOLEFINS (DE) | 2005-01-04 | — | — | US | disclosed |
| US-6787498-B2 | AS CATALYSTS FOR POLYMERIZATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2004-09-07 | — | — | US | disclosed |
| US-6699948-B2 | AS CATALYSTS FOR POLYMERIZATION OF OLEFINS | BASF AKTIENGESELLSCHAFT (DE) | 2004-03-02 | — | — | US | disclosed |
| US-20030055267-A1 | Monocyclopentadienyl complexes of chromium, molybdenum or tungsten | MIHAN SHAHRAM (DE) | 2003-03-20 | — | — | US | disclosed |
| EP-1288219-A2 | Monocyclopentadienyl complexes of chromium molybdenum or tungsten with a donor bridge | Basell Polyolefine GmbH (DE) | 2003-03-05 | — | — | EP | disclosed |
| US-20030036658-A1 | Monocyclopentadienyl complexes of chromium, molybdenum or tungsten | MIHAN SHAHRAM (DE) | 2003-02-20 | — | — | US | disclosed |
| US-20030036662-A1 | Monocyclopentadienyl complexes of chromium, molybdenum or tungsten | MIHAN SHAHRAM (DE) | 2003-02-20 | — | — | US | disclosed |
| EP-1212333-B1 | MONOCYCLOPENTADIENYL COMPLEXES OF CHROMIUM, MOLYBDENUM OR TUNGSTEN WITH A DONOR BRIDGE | BASELL POLYOLEFINE GMBH (DE) | 2003-02-12 | — | — | EP | disclosed |
| US-6437161-B1 | OLEFIN POLYMERIZATION CATALYSTS; SUBSTITUENT ON THE CYCLOPENTADIENYL RING CARRIES A DONOR FUNCTION WHICH IS BONDED RIGIDLY, NOT EXCLUSIVELY VIA SP3-HYBRIDIZED CARBON OR SILICON ATOMS, | BASF AKTIENGESELLSCHAFT (DE) | 2002-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030055267-A1 | Monocyclopentadienyl complexes of chromium, molybdenum or tungsten | SKIC3, ORC3, MCM3 | MAPT 3160/4885ALDH1A1 4462/4885NSD2 844/4885 |
| US-20030036662-A1 | Monocyclopentadienyl complexes of chromium, molybdenum or tungsten | SKIC3, ORC3, MCM3 | MAPT 3160/4885ALDH1A1 4462/4885NSD2 844/4885 |
| US-20030036658-A1 | Monocyclopentadienyl complexes of chromium, molybdenum or tungsten | SKIC3, ORC3, MCM3 | MAPT 3160/4885ALDH1A1 4462/4885NSD2 844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.