Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | TP53 | P04637 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4037029 | 0.90 | FABP4 (0.40) | KDM4EALDH1A1MAPTTP53SMN1; SMN2 | |
| SCHEMBL6131949 | 0.87 | KDM4E (0.49) | KDM4EALDH1A1MAPTTP53SMN1; SMN2 | |
| SCHEMBL1332988 | 0.85 | KDM4E (0.46) | KDM4EALDH1A1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL31435276 | 0.85 | KDM4E (0.46) | KDM4EALDH1A1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL1009498 | 0.84 | TSHR (0.48) | KDM4EALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL1011786 | 0.83 | DHODH (0.45) | KDM4EALDH1A1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL9899016 | 0.82 | NR4A2 (0.50) | KDM4EALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL9899201 | 0.82 | NR4A2 (0.46) | KDM4EALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL8510685 | 0.80 | PLA2G2A (0.51) | KDM4EALDH1A1MAPTHPGDMAPK1 | |
| SCHEMBL3151462 | 0.80 | MAPK8 (0.47) | ALDH1A1MEN1KMT2AGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214310-B1 | NOVEL PHOTOCHROMIC NAPHTHOPYRANS | TRANSITIONS OPTICAL INC (US) | 2005-04-27 | — | — | EP | disclosed |
| US-6348604-B1 | COMPOUNDS IN WHICH SELECTION AND PLACEMENT OF SUBSTITUENTS CONTROL WAVELENGTH AND/OR INTENSITY OF VISIBLE ABSORBANCE BANDS | PPG INDUSTRIES OHIO, INC. | 2002-02-19 | — | — | US | disclosed |