Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6131933 | 0.93 | KMT2A (0.34) | ALDH1A1KDM4EHPGDL3MBTL1GAA | |
| SCHEMBL6131950 | 0.88 | L3MBTL1 (0.41) | ALDH1A1TSHRL3MBTL1LMNAKMT2A | |
| SCHEMBL8919915 | 0.83 | MEN1 (0.38) | ALDH1A1KDM4ETSHRHPGDL3MBTL1 | |
| SCHEMBL7469925 | 0.82 | LMNA (0.38) | ALDH1A1KDM4ETSHRHPGDL3MBTL1 | |
| SCHEMBL6169985 | 0.81 | L3MBTL1 (0.43) | ALDH1A1KDM4EHPGDL3MBTL1LMNA | |
| SCHEMBL4597892 | 0.81 | ALDH1A1 (0.39) | ALDH1A1KDM4ETSHRHPGDL3MBTL1 | |
| SCHEMBL25606356 | 0.80 | PRKDC (0.35) | ALDH1A1KDM4ETSHRLMNADGAT1 | |
| SCHEMBL25716576 | 0.80 | EGFR (0.31) | MEN1KMT2APOLB | |
| SCHEMBL25605054 | 0.79 | ATM (0.32) | ALDH1A1KDM4ETSHRHPGDL3MBTL1 | |
| SCHEMBL6131970 | 0.79 | L3MBTL1 (0.45) | ALDH1A1KDM4EHPGDL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214310-B1 | NOVEL PHOTOCHROMIC NAPHTHOPYRANS | TRANSITIONS OPTICAL INC (US) | 2005-04-27 | — | — | EP | claimed |
| US-10758643-B2 | Mechanophoric medical product | AESCULAP AG (DE) | 2020-09-01 | — | — | US | disclosed |
| EP-3331581-B1 | MECHANOPHORIC MEDICAL PRODUKT | AESCULAP AG (DE) | 2020-07-08 | — | — | EP | disclosed |
| US-20190151502-A1 | Mechanophoric Medical Product | AESCULAP AG (DE) | 2019-05-23 | — | — | US | disclosed |
| EP-3331581-A1 | MECHANOPHORIC MEDICAL PRODUCT | Aesculap AG (DE) | 2018-06-13 | — | — | EP | disclosed |
| WO-2017025408-A1 | MECHANOPHORIC MEDICAL PRODUCT | AESCULAP AG (DE) | 2017-02-16 | — | — | WO | disclosed |
| EP-1214310-B1 | NOVEL PHOTOCHROMIC NAPHTHOPYRANS | TRANSITIONS OPTICAL INC (US) | 2005-04-27 | — | — | EP | disclosed |
| US-6348604-B1 | COMPOUNDS IN WHICH SELECTION AND PLACEMENT OF SUBSTITUENTS CONTROL WAVELENGTH AND/OR INTENSITY OF VISIBLE ABSORBANCE BANDS | PPG INDUSTRIES OHIO, INC. | 2002-02-19 | — | — | US | disclosed |