Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 7/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.54 |
| ▸ | HTR3E | A5X5Y0 | 5/20 | 0.54 |
| ▸ | HTR3B | O95264 | 5/20 | 0.54 |
| ▸ | HTR3A | P46098 | 5/20 | 0.54 |
| ▸ | HTR3D | Q70Z44 | 5/20 | 0.54 |
| ▸ | HTR3C | Q8WXA8 | 5/20 | 0.54 |
| ▸ | LTA4H | P09960 | 3/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HTR5A | P47898 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132525 | 0.86 | ADRB1 (0.61) | ADRB1SIGMAR1HTR3EHTR3BHTR3A | |
| Hydrochloric Acid SCHEMBL6132311 | 0.85 | ADRB1 (0.59) | ADRB1SIGMAR1HTR3EHTR3BHTR3A | |
| SCHEMBL613551 | 0.79 | OPRM1 (0.55) | SIGMAR1OPRM1OPRD1OPRK1OPRL1 | |
| Hydrochloric Acid SCHEMBL6132329 | 0.78 | OPRM1 (0.47) | SIGMAR1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL6132476 | 0.78 | USP2 (0.58) | OPRM1OPRD1OPRK1OPRL1USP2 | |
| Hydrochloric Acid SCHEMBL2420658 | 0.77 | OPRM1 (0.53) | SIGMAR1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL29638934 | 0.75 | OPRM1 (0.47) | SIGMAR1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL12122918 | 0.74 | OPRM1 (0.63) | OPRM1OPRD1OPRK1OPRL1TSHR | |
| SCHEMBL6132853 | 0.73 | ALDH1A1 (0.53) | OPRM1OPRD1OPRK1CYP2D6ALDH1A1 | |
| SCHEMBL13876257 | 0.73 | OPRM1 (0.59) | OPRM1OPRD1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |