Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 9/20 | 0.47 |
| ▸ | RARA | P10276 | 8/20 | 0.47 |
| ▸ | RARG | P13631 | 8/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132679 | 0.89 | NR1H4 (0.44) | RARBRARARARGMAPTCA2 | |
| SCHEMBL6132909 | 0.89 | NR1H4 (0.44) | RARBRARARARGMAPTCA2 | |
| SCHEMBL6132386 | 0.84 | MAPT (0.52) | MAPTCA2CA9S1PR1 | |
| SCHEMBL6132384 | 0.84 | MAPT (0.52) | MAPTCA2CA9S1PR1 | |
| SCHEMBL7420362 | 0.76 | ENPP3 (0.40) | RARBS1PR1S1PR3 | |
| SCHEMBL6133069 | 0.75 | TSHR (0.46) | RARBMAPTCA2CA9 | |
| SCHEMBL6133194 | 0.73 | HDAC4 (0.47) | MAPTCA2CA9 | |
| SCHEMBL6132885 | 0.73 | HDAC4 (0.47) | MAPTCA2CA9 | |
| SCHEMBL6132663 | 0.73 | RARB (0.55) | RARBMAPTNR1H4S1PR1S1PR3 | |
| SCHEMBL6132571 | 0.73 | RARB (0.55) | RARBMAPTNR1H4S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |