Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QRFPR | Q96P65 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | LOX | P28300 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.31 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.31 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GCGR | P47871 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL611198 | 0.75 | QRFPR (0.37) | QRFPRCYP2C19CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL612175 | 0.74 | ALDH1A1 (0.39) | QRFPRCYP2C19CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL612862 | 0.73 | QRFPR (0.39) | QRFPRLOXL2LOXUSP2HPGD | |
| SCHEMBL28104630 | 0.69 | QRFPR (0.56) | QRFPRCYP2D6USP2HPGDHSD17B10 | |
| SCHEMBL3244251 | 0.68 | HPGD (0.54) | QRFPRUSP2HPGDHSD17B10 | |
| SCHEMBL6447254 | 0.66 | CYP2C19 (0.61) | CYP2C19CYP1A2CYP3A4CYP2C9THPO | |
| SCHEMBL21234184 | 0.66 | HPGD (0.51) | QRFPRUSP2HPGDHSD17B10 | |
| SCHEMBL13630756 | 0.64 | PRMT6 (0.41) | QRFPRCYP3A4LOXL2LOXCYP2D6 | |
| SCHEMBL2151158 | 0.62 | BRD4 (0.42) | CYP2C19CYP1A2CYP3A4CYP2C9THPO | |
| SCHEMBL8254111 | 0.61 | LOXL2 (0.46) | LOXL2LOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120041038-A1 | AMINE DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS | ACUCELA INC. (US) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120041038-A1 | AMINE DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS | PDE6D, CLN6, AADAT | QRFPR 3141/4885CYP2C19 3315/4885CYP1A2 3048/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.