Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.63 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.63 |
| ▸ | HTR3E | A5X5Y0 | 4/20 | 0.63 |
| ▸ | HTR3B | O95264 | 4/20 | 0.63 |
| ▸ | HTR3A | P46098 | 4/20 | 0.63 |
| ▸ | HTR3D | Q70Z44 | 4/20 | 0.63 |
| ▸ | HTR3C | Q8WXA8 | 4/20 | 0.63 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | LTA4H | P09960 | 1/20 | 0.56 |
| ▸ | HTR6 | P50406 | 4/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | HTR5A | P47898 | 1/20 | 0.49 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6132971 | 0.98 | SIGMAR1 (0.61) | SIGMAR1ADRB1HTR3EHTR3BHTR3A | |
| SCHEMBL4252026 | 0.85 | ADRB1 (0.57) | SIGMAR1ADRB1HTR3EHTR3BHTR3A | |
| SCHEMBL7446491 | 0.85 | MBTD1 (0.55) | SIGMAR1ADRB1HTR3EHTR3BHTR3A | |
| SCHEMBL17931035 | 0.83 | SIGMAR1 (0.54) | SIGMAR1ADRB1HTR3EHTR3BHTR3A | |
| SCHEMBL38661103 | 0.82 | ADRB1 (0.53) | SIGMAR1ADRB1HTR3EHTR3BHTR3A | |
| SCHEMBL6618068 | 0.81 | ADRB1 (0.52) | SIGMAR1ADRB1HTR3EHTR3BHTR3A | |
| SCHEMBL241159 | 0.81 | DHFR (0.50) | SLC18A3KMT2ASMN1; SMN2USP2ALDH1A1 | |
| SCHEMBL8363020 | 0.81 | LMNA (0.49) | ADRB1SLC18A3HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL939776 | 0.81 | SLC18A3 (0.52) | SLC18A3HPGDKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL31612521 | 0.81 | MEN1 (0.61) | SIGMAR1ADRB1HTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |