Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6133004 | 0.85 | LMNA (0.38) | CNR2BRD9GSK3BDYRK1AMAPK14 | |
| SCHEMBL24255779 | 0.85 | GSK3B (0.37) | ITGA4ITGB7CNR2BRD9GSK3B | |
| SCHEMBL6133027 | 0.84 | ALDH1A1 (0.46) | DRD2ALDH1A1GFERSIGMAR1NAMPT | |
| SCHEMBL20262397 | 0.84 | ITGA4 (0.36) | ITGA4ITGB7CNR2BRD9GSK3B | |
| SCHEMBL6133587 | 0.80 | ALDH1A1 (0.44) | IDO1ALDH1A1GFERSIGMAR1NAMPT | |
| SCHEMBL22952416 | 0.79 | GSK3B (0.39) | ITGA4ITGB7CNR2BRD9GSK3B | |
| SCHEMBL2173526 | 0.77 | MAPK1 (0.41) | CNR2BRD9GSK3BDYRK1APTGDR2 | |
| SCHEMBL18283999 | 0.76 | CYP17A1 (0.39) | ITGA4ITGB7CNR2BRD9GSK3B | |
| SCHEMBL22322779 | 0.76 | CNR2 (0.40) | CNR2BRD9GSK3BDYRK1AMAPK14 | |
| SCHEMBL23009294 | 0.76 | ATR (0.40) | BRD9GSK3BDYRK1AMAPK14HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050004094-A1 | Cephem compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-06 | — | — | US | disclosed |
| WO-2004101571-A1 | CEPHEM COMPOUNDS | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2004-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004094-A1 | Cephem compounds | CEP170, C1S, CEPT1 | ITGA4 3612/4885ITGB7 2765/4885CNR2 236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.