Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | STK17B | O94768 | 1/20 | 0.37 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CKS1B | P61024 | 1/20 | 0.36 |
| ▸ | SKP1 | P63208 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6133027 | 0.92 | ALDH1A1 (0.46) | ALDH1A1GFERHTTNPSR1NAMPT | |
| SCHEMBL25056442 | 0.82 | ALDH1A1 (0.46) | ALDH1A1GFERHTTNPSR1NAMPT | |
| SCHEMBL6133119 | 0.80 | ITGA4 (0.38) | ALDH1A1GFERNAMPTSIGMAR1IDO1 | |
| SCHEMBL24255779 | 0.78 | GSK3B (0.37) | NAMPTIDO1 | |
| SCHEMBL6133004 | 0.76 | LMNA (0.38) | HTTTSHR | |
| SCHEMBL20262397 | 0.74 | ITGA4 (0.36) | ALDH1A1GFERMAPTTSHRIDO1 | |
| SCHEMBL5493771 | 0.74 | CCNC (0.41) | ALDH1A1GFERCCNCCDK8TDP1 | |
| SCHEMBL24192594 | 0.73 | CA12 (0.40) | ALDH1A1GFERMEN1GAAKMT2A | |
| SCHEMBL16118399 | 0.73 | CCNC (0.40) | ALDH1A1GFERCCNCCDK8MEN1 | |
| SCHEMBL2173526 | 0.73 | MAPK1 (0.41) | NAMPTIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050004094-A1 | Cephem compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004094-A1 | Cephem compounds | CEP170, C1S, CEPT1 | ALDH1A1 2105/4885GFER 1394/4885HTT 1106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.