SCHEMBL6134660

SCHEMBL6134660

O=C(O)N1CCC(OCC2CCCCC2)CC1

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CTSL P07711 1/20 0.45
CTSB P07858 1/20 0.45
CTSK P43235 1/20 0.45
LMNA P02545 1/20 0.41
EPHX2 P34913 1/20 0.41
SLC1A3 P43003 3/20 0.38
SLC1A2 P43004 3/20 0.38
SLC1A1 P43005 3/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
ALDH1A1 P00352 1/20 0.37
GPR119 Q8TDV5 3/20 0.35
F2 P00734 2/20 0.35
PRSS1 P07477 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NPC1 O15118 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20303253 0.98 CTSL (0.42) CTSLCTSBCTSKLMNAEPHX2
SCHEMBL19023658 0.91 LPL (0.39) CTSLCTSBCTSKEPHX2SLC1A3
SCHEMBL17220074 0.88 GPR119 (0.38) CTSLCTSBCTSKEPHX2SLC1A3
SCHEMBL29277070 0.83 ITGB3 (0.41) GPR119
SCHEMBL12813517 0.81 GPR119 (0.39) CTSLCTSBCTSKEPHX2ALDH1A1
SCHEMBL1241577 0.81 LIPG (0.42) CTSLCTSBCTSKSLC1A3SLC1A2
SCHEMBL27258938 0.79 CTSL (0.45) CTSLCTSBCTSKLMNAEPHX2
SCHEMBL12813505 0.79 GPR119 (0.38) ALDH1A1GPR119SMN1; SMN2
SCHEMBL26635122 0.77 GPR119 (0.58) GPR119
SCHEMBL18185631 0.77 CTSL (0.39) CTSLCTSBCTSKALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050261177-A1 Compound ASTELLAS PHARMA INC. (JP) 2005-11-24 US disclosed
EP-1366066-A2 CYCLOHEXAPEPTIDE HAVING ANTIMICROBIAL ACTIVITY FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2003-12-03 EP disclosed
WO-2002072621-A2 CYCLOHEXAPEPTIDE HAVING ANTIMICROBIAL ACTIVITY FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-09-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050261177-A1 Compound MANBA, MAN2B1, MAN2A1 CTSL 222/4885CTSB 1244/4885CTSK 2651/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.