Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | PRKACA | P17612 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL628152 | 0.77 | MEN1 (0.50) | MEN1KMT2ARAB9AALDH1A1HPGD | |
| SCHEMBL6153238 | 0.75 | ASIC3 (0.50) | MEN1KMT2ARAB9AALDH1A1HPGD | |
| SCHEMBL15671102 | 0.71 | MEN1 (0.47) | MEN1KMT2ARAB9AALDH1A1HPGD | |
| SCHEMBL1662450 | 0.67 | MEN1 (0.68) | MEN1KMT2ARAB9AALDH1A1HPGD | |
| SCHEMBL1274804 | 0.67 | ALDH1A1 (0.38) | MEN1KMT2ARAB9AALDH1A1HPGD | |
| SCHEMBL58442 | 0.66 | MEN1 (1.00) | MEN1KMT2ARAB9AALDH1A1HPGD | |
| SCHEMBL11666468 | 0.65 | SMN1; SMN2 (0.43) | MEN1KMT2ARAB9AALDH1A1HPGD | |
| SCHEMBL715046 | 0.65 | MEN1 (0.73) | MEN1KMT2ARAB9AALDH1A1HPGD | |
| SCHEMBL28598181 | 0.65 | RAB9A (0.73) | MEN1KMT2ARAB9AALDH1A1HPGD | |
| SCHEMBL16077969 | 0.64 | MEN1 (0.94) | MEN1KMT2ARAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082414-A2 | CONCOMITANT DRUGS OF A SULFONAMIDE AND ANOTHER THERAPEUTIC AGENT | ASTELLAS PHARMA INC. (JP) | 2005-09-09 | — | — | WO | disclosed |
| US-20050197376-A1 | Concomitant drugs | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2005-09-08 | — | — | US | disclosed |