Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 12/20 | 0.58 |
| ▸ | DRD3 | P35462 | 12/20 | 0.58 |
| ▸ | DRD4 | P21917 | 7/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6134728 | 1.00 | DRD2 (0.58) | DRD2DRD3DRD4MEN1KMT2A | |
| SCHEMBL5143973 | 0.80 | DRD2 (0.46) | DRD2DRD3DRD4MEN1KMT2A | |
| SCHEMBL6135104 | 0.78 | DRD2 (0.39) | DRD2DRD3DRD4HTR1ALMNA | |
| SCHEMBL6135102 | 0.78 | DRD2 (0.39) | DRD2DRD3DRD4HTR1ALMNA | |
| SCHEMBL14690785 | 0.78 | DRD3 (0.48) | DRD2DRD3DRD4ALDH1A1TSHR | |
| SCHEMBL338763 | 0.77 | DRD2 (0.58) | DRD2DRD3DRD4CYP2D6HTR1A | |
| SCHEMBL8768757 | 0.76 | DRD2 (0.42) | DRD2DRD3DRD4MEN1KMT2A | |
| SCHEMBL6134016 | 0.76 | DRD2 (0.48) | DRD2DRD3DRD4MEN1KMT2A | |
| SCHEMBL6134013 | 0.76 | DRD2 (0.48) | DRD2DRD3DRD4MEN1KMT2A | |
| SCHEMBL8768151 | 0.76 | DRD2 (0.52) | DRD2DRD3DRD4HTR1AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050090669-A1 | Aminoalcohol derivatives as beta-3 adrenergic receptor agonists | ASTELLAS PHARMA INC. (JP) | 2005-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090669-A1 | Aminoalcohol derivatives as beta-3 adrenergic receptor agonists | ADRB2, ADRB1, ADRB3 | DRD2 130/4885DRD3 113/4885DRD4 797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.