Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.52 |
| ▸ | DRD3 | P35462 | 9/20 | 0.52 |
| ▸ | DRD4 | P21917 | 4/20 | 0.52 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | ACHE | P22303 | 3/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768757 | 0.88 | DRD2 (0.42) | DRD2DRD3DRD4ACHE | |
| SCHEMBL8768766 | 0.82 | ACHE (0.45) | DRD2MTNR1AACHEMTNR1BSIGMAR1 | |
| SCHEMBL8767407 | 0.80 | TSHR (0.41) | GRIN1GRIN2BMTNR1ACA1CA2 | |
| SCHEMBL28019674 | 0.76 | CCR5 (0.47) | MTNR1AOPRM1 | |
| SCHEMBL6134727 | 0.76 | DRD2 (0.58) | DRD2DRD3DRD4GRIN2BHTR1A | |
| SCHEMBL6134728 | 0.76 | DRD2 (0.58) | DRD2DRD3DRD4GRIN2BHTR1A | |
| SCHEMBL5143748 | 0.75 | HSD11B1 (0.41) | — | |
| SCHEMBL5143634 | 0.74 | ALOX15 (0.48) | — | |
| SCHEMBL5146713 | 0.74 | HSD11B1 (0.42) | — | |
| SCHEMBL8767508 | 0.74 | ACHE (0.46) | MTNR1AACHEMTNR1BOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579833-B1 | ETHANOLAMINE DERIVATIVES WITH ANTI-POLLAKIURIA ACTIVITY | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-08-20 | — | — | EP | disclosed |