Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.42 |
| ▸ | DRD3 | P35462 | 3/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
| ▸ | UBE2M | P61081 | 6/20 | 0.39 |
| ▸ | DCUN1D1 | Q96GG9 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | MC5R | P33032 | 1/20 | 0.38 |
| ▸ | MC3R | P41968 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768151 | 0.88 | DRD2 (0.52) | DRD2DRD3DRD4ACHE | |
| SCHEMBL28019674 | 0.77 | CCR5 (0.47) | CCR5CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6134728 | 0.76 | DRD2 (0.58) | DRD2DRD3DRD4CYP2D6MEN1 | |
| SCHEMBL6134727 | 0.76 | DRD2 (0.58) | DRD2DRD3DRD4CYP2D6MEN1 | |
| SCHEMBL9456418 | 0.74 | AGER (0.58) | CCR5CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5144159 | 0.74 | HSD11B1 (0.43) | SLC6A4CETPUBE2MDCUN1D1MEN1 | |
| SCHEMBL27596342 | 0.73 | CCR5 (0.48) | CCR5CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5143973 | 0.72 | DRD2 (0.46) | DRD2DRD3DRD4CYP2D6SLC6A4 | |
| SCHEMBL5145400 | 0.72 | HSD11B1 (0.44) | SLC6A4CETPUBE2MDCUN1D1HSD11B1 | |
| SCHEMBL5136027 | 0.70 | MEN1 (0.51) | DRD3SLC6A2SLC6A4MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579833-B1 | ETHANOLAMINE DERIVATIVES WITH ANTI-POLLAKIURIA ACTIVITY | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-08-20 | — | — | EP | disclosed |